N-(4-methoxyphenyl)methyl-2-oxazolidinone

Base Information

• Chemical Name: N-(4-methoxyphenyl)methyl-2-oxazolidinone
• CAS No.: 450370-41-9
• Molecular Formula: C₁₁H₁₃NO₃
• Molecular Weight: 207.229
• Mol file: 450370-41-9.mol

Synonyms:N-(4-methoxyphenyl)methyl-2-oxazolidinone

Chemical Property of N-(4-methoxyphenyl)methyl-2-oxazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-methoxyphenyl)methyl-2-oxazolidinone

There total 6 articles about N-(4-methoxyphenyl)methyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

2-chloroethyl N-(4-methoxyphenyl)methylcarbamate → N-(4-methoxyphenyl)methyl-2-oxazolidinone (450370-41-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 6h; Heating;

Reference yield: 61.0%

1-(isocyanomethyl)-4-methoxybenzene (1197-58-6) + (vinylselenonyl)benzene → N-(4-methoxyphenyl)methyl-2-oxazolidinone (450370-41-9)

Guidance literature:

With water; caesium carbonate; In dichloromethane; at 40 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1002/chem.201505050

Reference yield: 60.0%

dimethylenecyclourethane (497-25-6) + 4-methoxy-benzaldehyde (123-11-5) → N-(4-methoxyphenyl)methyl-2-oxazolidinone (450370-41-9)

Guidance literature:

With triethylsilane; perrhenic acid anhydride; In dichloromethane; at 20 ℃; for 24h; chemoselective reaction;

DOI:10.1039/c2cc33185c

upstream raw materials:

4-methoxy-benzylamine

dimethylenecyclourethane

4-methoxy-benzaldehyde

1-(isocyanomethyl)-4-methoxybenzene

Downstream raw materials:

dimethylenecyclourethane