S-cyclohexyl 4-methylbenzothioate

Base Information

• Chemical Name: S-cyclohexyl 4-methylbenzothioate
• CAS No.: 105314-81-6
• Molecular Formula: C₁₄H₁₈OS
• Molecular Weight: 234.362
• Mol file: 105314-81-6.mol

Synonyms:S-cyclohexyl 4-methylbenzothioate

Chemical Property of S-cyclohexyl 4-methylbenzothioate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of S-cyclohexyl 4-methylbenzothioate

There total 8 articles about S-cyclohexyl 4-methylbenzothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

Cyclohexanethiol (1569-69-3) + p-Toluic acid (99-94-5) → S-cyclohexyl 4-methylbenzothioate (105314-81-6)

Guidance literature:

With 1H-imidazole; iodine; chloro-diphenylphosphine; In acetonitrile; for 2h; Reflux;

DOI:10.1016/j.tet.2010.10.022

Reference yield: 89.0%

O-(tert-butyl) S-cyclohexyl thiocarbonate (162222-10-8) + p-tolyl triflate (29540-83-8) → S-cyclohexyl 4-methylbenzothioate (105314-81-6)

Guidance literature:

With 1,10-Phenanthroline; (1,2-dimethoxyethane)dichloronickel(II); tetrabutyl-ammonium chloride; magnesium bromide; zinc; In N,N-dimethyl acetamide; at 80 ℃; for 12h; chemoselective reaction; Schlenk technique; Inert atmosphere; Glovebox;

DOI:10.1021/acs.orglett.1c00313

Reference yield: 52.0%

carbon monoxide (201230-82-2) + N-cyclohexylidene-1-phenylethylamine (6115-06-6) + para-thiocresol (106-45-6) → S-(p-tolyl) p-methylbenzothioathe (39248-95-8) + (1-phenylethyl)(4-methylphenyl)sulfide (24422-69-3) + N-(p-methylbenzoyl)-α-methylbenzyl amine (17537-45-0) + S-cyclohexyl 4-methylbenzothioate (105314-81-6)

Guidance literature:

dicobalt octacarbonyl; In benzene; at 180 ℃; under 56886.3 - 67229.2 Torr; Further byproducts given; stainless steel autoclave;

upstream raw materials:

carbon monoxide

N-cyclohexylidene-1-phenylethylamine

para-thiocresol

Cyclohexanethiol