4-BroMo-2,6-diMethoxybenzaldehyde

Base Information

• Chemical Name: 4-BroMo-2,6-diMethoxybenzaldehyde
• CAS No.: 1354050-38-6
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.073
• Hs Code.: 2913000090
• Mol file: 1354050-38-6.mol

Synonyms:4-bromo-2,6-dimethoxy-benzaldehyde

Chemical Property of 4-BroMo-2,6-diMethoxybenzaldehyde

Chemical Property:

• Boiling Point: 333.6±42.0 °C(Predicted)
• Density: 1.482±0.06 g/cm3 (20 oC 760 Torr)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Bromo-2,6-dimethoxybenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BroMo-2,6-diMethoxybenzaldehyde

There total 3 articles about 4-BroMo-2,6-diMethoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Dichloromethyl methyl ether (4885-02-3) + 1-bromo-3,5-dimethoxybenzene (20469-65-2) → 4-bromo-2,6-dimethoxy-benzaldehyde (1354050-38-6) + 2-bromo-4,6-dimethoxybenzaldehyde (81574-69-8)

Guidance literature:

Dichloromethyl methyl ether; 1-bromo-3,5-dimethoxybenzene; With titanium tetrachloride; In dichloromethane; at 0 - 20 ℃; for 4h;

With hydrogenchloride; In dichloromethane; water; at 0 ℃; for 0.25h;

DOI:10.1039/C7OB00118E

Reference yield:

methanol (67-56-1) + 4-bromo-2,6-difluorobenzaldehyde (537013-51-7) → 4-bromo-2,6-dimethoxy-benzaldehyde (1354050-38-6) + 4-bromo-2-fluoro-6-methoxy-benzaldehyde (856767-09-4)

Guidance literature:

With potassium hydroxide; at 20 - 55 ℃; for 1.33333h;

Reference yield:

1-bromo-3,5-dimethoxybenzene (20469-65-2) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 4-bromo-2,6-dimethoxy-benzaldehyde (1354050-38-6)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In diethyl ether; at 0 - 20 ℃; for 6h;

DOI:10.1021/jm3008213

upstream raw materials:

1-bromo-3,5-dimethoxybenzene

N,N-dimethyl-formamide

methanol

4-bromo-2,6-difluorobenzaldehyde

Downstream raw materials:

C₁₈H₁₅BrO₄

4-bromo-2,6-dimethoxy-benzoic acid

Refernces

• 1、 Yang, Woo-Ram,Choi, Yong-Sung,Jeong, Jin-Hyun. "Efficient synthesis of polymethoxyselenoflavones via regioselective direct C-H arylation of selenochromones". supporting information. p. 3074 - 3083. Retrieved 2017/04/10.
• 2、 -. "HERBICIDALLY ACTIVE (ALKYNYL-PHENYL)-SUBSTITUTED CYCLIC DIONE COMPOUNDS AND DERIVATIVES THEREOF". Page/Page column 121-122. . Retrieved 2014/12/12.