C₁₇H₁₇NO₂

Base Information

• Chemical Name: C₁₇H₁₇NO₂
• CAS No.: 349426-61-5
• Molecular Formula: C₁₇H₁₇NO₂
• Molecular Weight: 267.327
• Mol file: 349426-61-5.mol

Synonyms:C₁₇H₁₇NO₂

Chemical Property of C₁₇H₁₇NO₂

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of C₁₇H₁₇NO₂

There total 4 articles about C₁₇H₁₇NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

diisopropyl (2-((4-methoxybenzyl)amino)-2-oxoethyl)phosphonate (1426294-38-3) + girard's reagent T (123-46-6) + benzaldehyde (100-52-7) → C17H17NO2 (349426-61-5) + di-isopropylphosphonate anion + 2-(2-benzylidenehydrazinyl)-N,N,N-trimethyl-2-oxoethaneaminium chloride (6958-22-1)

Guidance literature:

diisopropyl (2-((4-methoxybenzyl)amino)-2-oxoethyl)phosphonate; benzaldehyde; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 6h;

girard's reagent T; In tetrahydrofuran; methanol; stereoselective reaction;

DOI:10.1021/co400003d

Reference yield:

Cinnamic acid (621-82-9) + 4-methoxy-benzylamine (2393-23-9) → C17H17NO2 (349426-61-5)

Guidance literature:

With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;

DOI:10.1021/jacs.0c09654

Reference yield:

3-phenyl-propenal (104-55-2) → C17H17NO2 (349426-61-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / toluene / 4 h / 100 °C / Inert atmosphere

2: toluene / 18 h / 40 °C / Inert atmosphere

With 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; 1,3-bis-(2,6-diisopropylphenyl)-imidazol-2-ylidene; In toluene;

DOI:10.1039/c4ra04012k

upstream raw materials:

diisopropyl (2-((4-methoxybenzyl)amino)-2-oxoethyl)phosphonate

girard's reagent T

benzaldehyde

3-phenyl-propenal

Downstream raw materials:

cinnamamide