Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester

Base Information

• Chemical Name: Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester
• CAS No.: 123059-44-9
• Molecular Formula: C₁₈H₂₇ClOS₂
• Molecular Weight: 358.997
• Mol file: 123059-44-9.mol

Synonyms:Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester

Chemical Property of Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester

There total 1 articles about Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

Nonane-1-thiol (1455-21-6) + 4-chlorobenzaldehyde (104-88-1) + tiolacetic acid (507-09-5) → Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester (123059-44-9)

Guidance literature:

With zinc(II) iodide; In dichloromethane; for 2h; Heating;

DOI:10.1016/S0040-4039(00)82440-5

Reference yield: 94.0%

2-bromo-N,N-dimethylethanamide (5468-77-9) + Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester (123059-44-9) → 2-[(4-Chloro-phenyl)-nonylsulfanyl-methylsulfanyl]-N,N-dimethyl-acetamide (123059-50-7)

Guidance literature:

With potassium carbonate; In methanol; butanone; at -10 ℃; for 1.5h;

DOI:10.1016/S0040-4039(00)82440-5

Reference yield:

ethyl bromide (74-96-4) + Thioacetic acid S-[(4-chloro-phenyl)-nonylsulfanyl-methyl] ester (123059-44-9) → 1-Chloro-4-(ethylsulfanyl-nonylsulfanyl-methyl)-benzene (123059-52-9)

Guidance literature:

With sodium methylate; Yield given. Multistep reaction; 1) THF, -80 deg C, 5 min, 2) 20 min, -80 deg C to room temp.;

DOI:10.1016/S0040-4039(00)82440-5

upstream raw materials:

Nonane-1-thiol

4-chlorobenzaldehyde

tiolacetic acid

Downstream raw materials:

1-Chloro-4-(ethylsulfanyl-nonylsulfanyl-methyl)-benzene

2-[(4-Chloro-phenyl)-nonylsulfanyl-methylsulfanyl]-N,N-dimethyl-acetamide

3-[(4-Chloro-phenyl)-nonylsulfanyl-methylsulfanyl]-propionic acid methyl ester