2,3,4,5-Tetrafluorobenzamide

Base Information

• Chemical Name: 2,3,4,5-Tetrafluorobenzamide
• CAS No.: 16582-94-8
• Molecular Formula: C7H3 F4 N O
• Molecular Weight: 193.101
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID50380203
• Nikkaji Number: J1.253.273C
• Wikidata: Q82170318
• Mol file: 16582-94-8.mol

Synonyms:2,3,4,5-Tetrafluorobenzamide;16582-94-8;MFCD01631457;tetrafluorobenzamide;SCHEMBL829400;DTXSID50380203;AKOS009139170;AS-8770;CS-0313273;E76983

Chemical Property of 2,3,4,5-Tetrafluorobenzamide

Chemical Property:

• Vapor Pressure: 11.1mmHg at 25°C
• Melting Point: 132-134°C
• Refractive Index: 1.474
• Boiling Point: 127.6°Cat760mmHg
• Flash Point: 30.9°C
• PSA: 43.09000
• Density: 1.545g/cm³
• LogP: 2.04220
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 193.01507637
• Heavy Atom Count: 13
• Complexity: 213

Purity/Quality:

99%, ^*data from raw suppliers

2,3,4,5-Tetrafluorobenzamide ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi:Irritant
• Statements: R36/37/38:
• Safety Statements: S26-36:

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=C(C(=C(C(=C1F)F)F)F)C(=O)N

Technology Process of 2,3,4,5-Tetrafluorobenzamide

There total 7 articles about 2,3,4,5-Tetrafluorobenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

methanol (67-56-1) + methylamine (74-89-5) + 3-methyl-5-(2,3,4,5-tetrafluorophenyl)-1,2,4-oxadiazole (740817-47-4) → 1,3-dimethyl-5-(2,3,4,5-tetrafluoro-phenyl)-1H-[1,2,4]triazole + 2,3,4,5-tetrafluoro-N-(1-methoxyimino-ethyl)-benzamide + 2,3,4,5-tetrafluorobenzamide (16582-94-8) + 5,6,7,8-tetrafluoro-2-methyl-3H-quinazolin-4-one

Guidance literature:

With oxygen; for 3h; Irradiation;

DOI:10.3987/COM-04-10255

Reference yield: 34.0%

methanol (67-56-1) + propylamine (107-10-8,42939-71-9) + 3-methyl-5-(2,3,4,5-tetrafluorophenyl)-1,2,4-oxadiazole (740817-47-4) → 2,3,4,5-tetrafluoro-N-(1-methoxyimino-ethyl)-benzamide + 3-methyl-1-propyl-5-(2,3,4,5-tetrafluoro-phenyl)-1H-[1,2,4]triazole + 2,3,4,5-tetrafluorobenzamide (16582-94-8) + 5,6,7,8-tetrafluoro-2-methyl-3H-quinazolin-4-one

Guidance literature:

With oxygen; for 3h; Irradiation;

DOI:10.3987/COM-04-10255

Reference yield:

1,2,3,4-tetrafluorobenzene (551-62-2) → 2,3,4,5-tetrafluorobenzamide (16582-94-8)

Guidance literature:

Multi-step reaction with 3 steps

1: Br₂, SO₃/H₂SO₄

2: dimethylformamide / Heating

3: H₂SO₄

With sulfuric acid; sulfur trioxide; bromine; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4020(01)92570-0

upstream raw materials:

2,3,4,5-tetrafluorobenzonitrile

2,3,4,5,6-pentafluorobenzamide

methanol

propylamine

Downstream raw materials:

2,3,4,5-tetrafluorobenzoic acid

2,3,4,5-tetrafluorobenzonitrile

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 16582-94-8 Benzamide,2,3,4,5-tetrafluoro-

Send

Send

Metric Ton KG G Pound L ML

Send

Send