CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II)

Base Information

• Chemical Name: CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II)
• CAS No.: 14872-21-0
• Molecular Formula: C₁₀H₁₀Cl₂N₂Pt
• Molecular Weight: 424.189
• Mol file: 14872-21-0.mol

Synonyms:Dichlorobis(pyridine)platinum

Chemical Property of CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II)

Chemical Property:

• Melting Point: 282-288 °C(lit.)
• Boiling Point: 115.3°Cat760mmHg
• Flash Point: 20°C
• PSA: 0.00000
• Density: g/cm³
• LogP: 1.51230
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

98%Min ^*data from raw suppliers

Dichlorobis(pyridine)platinum 95+% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II)

There total 98 articles about CIS-DICHLOROBIS(PYRIDINE)PLATINUM(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

trans-tetrachlorobis(pyridine)platinum(II) (16893-32-6,17100-03-7,19306-93-5) + methyl (triphenylphosphoranylidene)acetate (21204-67-1,2605-67-6) → trans-dichlorobis(pyridine)platinum(II) (14024-97-6,14872-21-0,15227-42-6) + (2-methoxy-2-oxoethyl)triphenylphosphonium chloride (2181-97-7) + Triphenylphosphine oxide (791-28-6)

Guidance literature:

In dichloromethane; Ph3P=CHCO2Me was added to soln. Pt(IV) complex in CH2Cl2, react. mixt. was kept at room temp. for 3 h; solvent was evapd., residue was chromed. on silica using CH2Cl2/Et2O (9:1) as eluent;

DOI:10.1021/ic000769c

Reference yield: 95.0%

pyridine (110-86-1) + potassium tetrachloroplatinate → trans-dichlorobis(pyridine)platinum(II) (14024-97-6,14872-21-0,15227-42-6)

Guidance literature:

pyridine; potassium tetrachloroplatinate; In water; for 1h; Heating / reflux;

With hydrogenchloride; In water; at 4 ℃; for 17h;

Reference yield: 92.0%

pyridine (110-86-1) + hydrogenchloride (7647-01-0,15364-23-5) + potassium tetrachloroplatinate(II) (10025-99-7) → trans-dichlorobis(pyridine)platinum(II) (14024-97-6,14872-21-0,15227-42-6)

Guidance literature:

pyridine; potassium tetrachloroplatinate(II); In water; at 85 ℃; for 1.5h;

hydrogenchloride; In water; at 75 ℃;

DOI:10.1039/d1dt01730f

upstream raw materials:

pyridine

thallous 2,3,5,6-tetrafluorobenzoate

Hexafluorobenzene

(SP-4-3)-dichlorido(N,N-dimethyl-ethane-1,2-diamine)platinum(II)

Downstream raw materials:

platinum

trans-dichlorobis(pyridine)platinum(II)

cis-dichlorobis(dimethylsulfoxide)platinum(II)

cis-[PtCl₂(C₅H₅N)(Me₂SO)]

Refernces

• 1、 Lewis, Nerissa A.,Pakhomova, Svetlana,Marzilli, Patricia A.,Marzilli, Luigi G.. "Synthesis and Characterization of Pt(II) Complexes with Pyridyl Ligands: Elongated Octahedral Ion Pairs and Other Factors Influencing 1H NMR Spectra". supporting information. p. 9781 - 9793. Retrieved 2017/08/26.
• 2、 -. "Compound with antitumor activity, and preparation method and application thereof". Paragraph 0094; 0095; 0096; 0100. . Retrieved 2017/12/28.