2'-Guanylic acid

Base Information

• Chemical Name: 2'-Guanylic acid
• CAS No.: 130-50-7
• Molecular Formula: C10H14 N5 O8 P
• Molecular Weight: 363.224
• Mol file: 130-50-7.mol

Synonyms:2'-GMP;Guanosine 2'-(dihydrogen phosphate); Guanosine 2'-monophosphate; Guanosine2'-phosphate

Chemical Property of 2'-Guanylic acid

Chemical Property:

• Boiling Point: 908.4°Cat760mmHg
• Flash Point: 503.2°C
• PSA: 215.85000
• Density: 2.47g/cm³
• LogP: -1.98850

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2'-Guanylic acid

There total 10 articles about 2'-Guanylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Phosphoric acid (2R,3S,4R,5R)-5-(2-amino-6-oxo-1,6-dihydro-purin-9-yl)-4-hydroxy-2-hydroxymethyl-tetrahydro-furan-3-yl ester (2R,3S,4R,5R)-5-(6-amino-purin-9-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethyl ester (6554-00-3) → guanosine 3'-monophosphate (117-68-0) + guanosine 2',3'-cyclic monophosphate (634-02-6) + guanosine 2'-monophosphate (130-50-7) + adenosine (58-61-7)

Guidance literature:

With deuteriated sodium hydroxide; sodium chloride; In water-d2; at 24.84 ℃; pH=10.70 - 13.60; Further Variations:; pH-values; Kinetics;

DOI:10.1021/jo026545o

Reference yield:

[3']guanylic acid guanosin-5'-yl ester (3353-33-1) → guanosine 3'-monophosphate (117-68-0) + guanosine 2',3'-cyclic monophosphate (634-02-6) + guanosine 2'-monophosphate (130-50-7)

Guidance literature:

With deuteriated sodium hydroxide; sodium chloride; In water-d2; at 24.84 ℃; pH=10.96 - 13.58; Further Variations:; pH-values; Kinetics;

DOI:10.1021/jo026545o

Reference yield:

2-amino-1,9-dihydro-6H-purin-6-one (73-40-5) + D-ribose (50-69-1) → Guanosine 5'-monophosphate (85-32-5) + guanosine 3'-monophosphate (117-68-0) + guanosine 2'-monophosphate (130-50-7) + G (118-00-3)

Guidance literature:

With Sodium trimetaphosphate; In water; at 20 ℃; for 264h;

DOI:10.1039/c1cc10310e

upstream raw materials:

guanosine 2',3'-cyclic monophosphate

[3']guanylic acid guanosin-5'-yl ester

O-phenyl phosphorodichloridate

G

Downstream raw materials:

guanosine 2',3'-cyclic monophosphate

8-bromoguanosine 2'-phosphate