1,4-Dimethylpyrrolidin-2-one

Base Information

• Chemical Name: 1,4-Dimethylpyrrolidin-2-one
• CAS No.: 2555-04-6
• Molecular Formula: C6H11 N O
• Molecular Weight: 113.159
• Hs Code.: 2933790090
• DSSTox Substance ID: DTXSID40560012
• Mol file: 2555-04-6.mol

Synonyms:1,4-Dimethylpyrrolidin-2-one;2555-04-6;1,4-Dimethylpyrrolid-2-one;1,4-Dimethyl-2-pyrrolidone;2-Pyrrolidinone, 1,4-dimethyl-;(4S)-1,4-dimethylpyrrolidin-2-one;SCHEMBL435095;1, 4-dimethylpyrrolidin-2-one;12-hydroxy-octadec-9-enoic acid;DTXSID40560012;MFCD09800606;AKOS015897896;AM86073;F18257;A853158;1,4-DIMETHYLPYRROLIDIN-2-ONE;2058436-33-0

Chemical Property of 1,4-Dimethylpyrrolidin-2-one

Chemical Property:

• Vapor Pressure: 0.376mmHg at 25°C
• Refractive Index: 1.455
• Boiling Point: 197.6°Cat760mmHg
• PKA: -0.37±0.40(Predicted)
• Flash Point: 85.2°C
• PSA: 20.31000
• Density: 0.973g/cm³
• LogP: 0.42250
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 113.084063974
• Heavy Atom Count: 8
• Complexity: 111

Purity/Quality:

97% ^*data from raw suppliers

1,4-Dimethylpyrrolidin-2-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC(=O)N(C1)C
• Uses: 1,4-Dimethylpyrrolidin-2-one can be usd to produce fine particles and fine particles-?dispersed solution.

Technology Process of 1,4-Dimethylpyrrolidin-2-one

There total 7 articles about 1,4-Dimethylpyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methylenesuccinic acid (97-65-4,25119-64-6) + methylamine (74-89-5) → 1,3-dimethyl-pyrrolidin-2-one (19597-07-0) + N-methyl-3-methylpyrrolidine (45470-22-2) + 1,4-dimethyl-2-pyrrolidone (2555-04-6) + trimethylamine (75-50-3)

Guidance literature:

With hydrogen; 5% active carbon-supported ruthenium; In water; at 20 - 200 ℃; for 24h; under 37503.8 - 150015 Torr; Product distribution / selectivity; Autoclave;

Reference yield:

2-methylenesuccinic acid (97-65-4,25119-64-6) + methylamine (74-89-5) → 3-methyl-2-pyrrolidinone (2555-05-7) + 1,3-dimethyl-pyrrolidin-2-one (19597-07-0) + 1,4-dimethyl-2-pyrrolidone (2555-04-6) + methyl-succinic acid bis-methylamide + trimethylamine (75-50-3)

Guidance literature:

With hydrogen; 5% rhodium-on-charcoal; In water; at 20 - 200 ℃; for 72h; under 37503.8 - 187519 Torr; Product distribution / selectivity; Autoclave;

Reference yield:

2-methylenesuccinic acid (97-65-4,25119-64-6) + methylamine (74-89-5) → 1,3-dimethyl-pyrrolidin-2-one (19597-07-0) + 1,3-Dimethyl-2,5-pyrrolidindion (15542-96-8,211682-20-1) + 1,4-dimethyl-2-pyrrolidone (2555-04-6)

Guidance literature:

With hydrogen; 5% rhodium-on-charcoal; In water; at 20 ℃; for 24h; under 37503.8 - 150015 Torr; Product distribution / selectivity; Autoclave;

upstream raw materials:

2-methylenesuccinic acid

methylamine

1-Methyl-5-oxo-3-pyrrolidinecarboxylic Acid