4'-Fluoro-2,2-dimethoxyacetophenone

Base Information

Chemical Name:4'-Fluoro-2,2-dimethoxyacetophenone
CAS No.:21983-80-2
Molecular Formula:C10H11 F O3
Molecular Weight:198.194
Hs Code.:2914700090
European Community (EC) Number:407-500-1
DSSTox Substance ID:DTXSID20472826
Wikidata:Q82301994
Mol file:21983-80-2.mol

Synonyms:21983-80-2;4'-FLUORO-2,2-DIMETHOXYACETOPHENONE;DTXSID20472826;AKOS018048756

Suppliers and Price of 4'-Fluoro-2,2-dimethoxyacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4'-Fluoro-2,2-dimethoxyacetophenone

Chemical Property:

PSA：35.53000
LogP:1.62730
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:198.06922237
Heavy Atom Count:14
Complexity:184

Purity/Quality:: 99.9% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 43-52/53
Safety Statements: 24-37-61

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(C(=O)C1=CC=C(C=C1)F)OC

Technology Process of 4'-Fluoro-2,2-dimethoxyacetophenone

There total 4 articles about 4'-Fluoro-2,2-dimethoxyacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 1401816-27-0
N-trimethoxy-N-methyl-acetamide

: 130387-74-5
4-fluorophenylmagnesium chloride

: 21983-80-2
1,1-dimethoxy-2-(4-fluorophenyl)-ethan-2-one

Guidance literature:: In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.3390/molecules171213864

Reference yield: 85.0%

: 67-56-1
methanol

: 403-42-9
1-(4-fluorophenyl)ethanone

: 21983-80-2
1,1-dimethoxy-2-(4-fluorophenyl)-ethan-2-one

Guidance literature:: With iodine; at 90 ℃; for 9h;

Reference yield:

: 67-56-1
methanol

: 403-32-7
(4-fluorophenyl)glyoxal

: 21983-80-2
1,1-dimethoxy-2-(4-fluorophenyl)-ethan-2-one

Guidance literature:: With thionyl chloride; In pyridine; at 20 ℃; Inert atmosphere; Molecular sieve; Cooling with ice; Schlenk technique;
DOI:10.1002/adsc.201700175