R-Hydroxyzine

Base Information

Chemical Name:R-Hydroxyzine
CAS No.:189298-46-2
Molecular Formula:C₂₁H₂₇ClN₂O₂
Molecular Weight:374.911
Hs Code.:
UNII:E94KVV98R9
Nikkaji Number:J3.571.388C
Mol file:189298-46-2.mol

Synonyms:R-Hydroxyzine;Hydroxyzine, (R)-;E94KVV98R9;UNII-E94KVV98R9;2-(2-(4-((R)-(4-Chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)ethanol;Ethanol, 2-(2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, (R)-;Ethanol, 2-(2-(4-((R)-(4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-;189298-46-2;(R)-Hydroxyzine;SCHEMBL4492;PDSP1_000267;PDSP2_000266;J3.571.388C

Suppliers and Price of R-Hydroxyzine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of R-Hydroxyzine

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:374.1761058
Heavy Atom Count:26
Complexity:376

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl
Isomeric SMILES:C1CN(CCN1CCOCCO)[C@H](C2=CC=CC=C2)C3=CC=C(C=C3)Cl

Technology Process of R-Hydroxyzine

There total 4 articles about R-Hydroxyzine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 28022-43-7
p-chlorobenzhydrylamine

: 111-42-2
2,2'-iminobis[ethanol]

: 111-46-6
diethylene glycol

: 68-88-2,147152-22-5,147152-23-6,189298-46-2
hydroxizine

Guidance literature:: p-chlorobenzhydrylamine; 2,2'-iminobis[ethanol]; With iridium graphene nanostructured catalyst; at 110 ℃; Schlenk technique; Inert atmosphere; Green chemistry;

diethylene glycol; at 110 ℃; Inert atmosphere; Schlenk technique; Green chemistry;
DOI:10.1039/d1ra09052f