(S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Base Information

Chemical Name:(S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one
CAS No.:428874-28-6
Molecular Formula:C₃₄H₄₃NO₄Si
Molecular Weight:557.805
Hs Code.:

Synonyms:(S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Suppliers and Price of (S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

There total 8 articles about (S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 253143-32-7
(S)-4-Benzyl-3-[(S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-hexanoyl]-oxazolidin-2-one

: 74-88-4
methyl iodide

: 428874-28-6
(S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Guidance literature:: (S)-4-Benzyl-3-[(S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-hexanoyl]-oxazolidin-2-one; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at -78 - -40 ℃; Further stages.;
DOI:10.1021/ja020091v

Reference yield:

: 253143-30-5
(R)-4-benzyl-3-((S)-2-ethylpent-4-enoyl)oxazolidin-2-one

: 428874-28-6
(S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 8 steps

1.1: lithium borohydride / diethyl ether; H₂O / 0.5 h / 0 °C

2.1: 20.6 g / imidazole; 4 Angstroem molecular sieves / petroleum ether; diethyl ether; dimethylformamide / 20 °C

3.1: 9-BBN / tetrahydrofuran / 4 h / 20 °C

3.2: 92 percent / sodium hydroxide; hydroden peroxide / tetrahydrofuran; H₂O / 0 - 20 °C

4.1: pyridinium dichromate / CH₂Cl₂ / 0.5 h

5.1: 6.9 g / sodium chlorite; sulfamic acid / tetrahydrofuran; H₂O / 0 - 20 °C

6.1: triethylamine / tetrahydrofuran / -78 - 0 °C

7.1: 5.53 g / lithium chloride / tetrahydrofuran / 20 °C

8.1: sodium hexamethyldisilazide / tetrahydrofuran / 1 h / -78 °C

8.2: 95 percent / tetrahydrofuran / -78 - -40 °C

With 1H-imidazole; sodium chlorite; dipyridinium dichromate; lithium borohydride; 9-borabicyclo[3.3.1]nonane dimer; 4 A molecular sieve; aminosulfonic acid; sodium hexamethyldisilazane; triethylamine; lithium chloride; In tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; Petroleum ether;
DOI:10.1021/ja020091v

Reference yield:

: 253143-31-6
4-(tert-butyl-diphenyl-silanyloxymethyl)-hexan-1-ol

: 428874-28-6
(S)-4-Benzyl-3-[(2S,4S)-4-(tert-butyl-diphenyl-silanyloxymethyl)-2-methyl-hexanoyl]-oxazolidin-2-one

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridinium dichromate / CH₂Cl₂ / 0.5 h

2.1: 6.9 g / sodium chlorite; sulfamic acid / tetrahydrofuran; H₂O / 0 - 20 °C

3.1: triethylamine / tetrahydrofuran / -78 - 0 °C

4.1: 5.53 g / lithium chloride / tetrahydrofuran / 20 °C

5.1: sodium hexamethyldisilazide / tetrahydrofuran / 1 h / -78 °C

5.2: 95 percent / tetrahydrofuran / -78 - -40 °C

With sodium chlorite; dipyridinium dichromate; aminosulfonic acid; sodium hexamethyldisilazane; triethylamine; lithium chloride; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/ja020091v