3-(3-Fluorophenyl)propan-1-OL

Base Information

• Chemical Name: 3-(3-Fluorophenyl)propan-1-OL
• CAS No.: 156868-83-6
• Molecular Formula: C9H11 F O
• Molecular Weight: 154.184
• DSSTox Substance ID: DTXSID60565822
• Wikidata: Q82451109
• Mol file: 156868-83-6.mol

Synonyms:3-(3-FLUOROPHENYL)PROPAN-1-OL;156868-83-6;Benzenepropanol, 3-fluoro-;3-(3-FLUORO-PHENYL)-PROPAN-1-OL;C9H11FO;SCHEMBL81108;3-(3-Fluorophenyl)-1-propanol;DTXSID60565822;VXWCHEGRBQAVQL-UHFFFAOYSA-N;AB3824;MFCD09028717;AKOS005217827;SB83959;AS-44737;CS-0111676;EN300-1241226

Chemical Property of 3-(3-Fluorophenyl)propan-1-OL

Chemical Property:

• Vapor Pressure: 0.03mmHg at 25°C
• Refractive Index: 1.509
• Boiling Point: 234.162°C at 760 mmHg
• Flash Point: 116.828°C
• PSA: 20.23000
• Density: 1.098g/cm³
• LogP: 1.75060
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 154.079393132
• Heavy Atom Count: 11
• Complexity: 106

Purity/Quality:

97% ^*data from raw suppliers

3-(3-Fluorophenyl)propan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)F)CCCO

Technology Process of 3-(3-Fluorophenyl)propan-1-OL

There total 15 articles about 3-(3-Fluorophenyl)propan-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-(3-fluorophenyl)propionic acid (458-45-7) → 3-(3-fluorophenyl)propan-1-ol (156868-83-6)

Guidance literature:

With LiAlH₄; In tetrahydrofuran;

Reference yield: 82.0%

methyl 3-(3-fluorophenyl)propanoate (425704-52-5) → 3-(3-fluorophenyl)propan-1-ol (156868-83-6)

Guidance literature:

methyl 3-(3-fluorophenyl)propanoate; With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 - 0 ℃; Inert atmosphere;

With Rochelle's salt; In dichloromethane; water; Inert atmosphere;

Reference yield:

C12H13FO4 → 3-(3-fluorophenyl)propan-1-ol (156868-83-6)

Guidance literature:

C₁₂H₁₃FO₄; With sodium tetrahydroborate; In tetrahydrofuran; water; at 0 ℃; for 0.166667h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; pH=2;

upstream raw materials:

oxirane

1-(Bromomethyl)-3-fluorobenzene

methyl 3-(3-fluorophenyl)propanoate

3-Fluorocinnamic acid

Downstream raw materials:

1-(3-bromo-propyl)-3-fluoro-benzene

(3Z,11Z,16Z)-(5S,6S,7R,8R,9S,13S,14S,15S)-8,14-Bis-(tert-butyl-dimethyl-silanyloxy)-19-(3-fluoro-phenyl)-5,7,9,11,13,15-hexamethyl-nonadeca-1,3,11,16-tetraen-6-ol

3-fluoro-α,α-dimethylbenzenebutanol

3-fluoro-α-methylbenzenebutanol