2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Base Information

Chemical Name:2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide
CAS No.:1051397-27-3
Molecular Formula:C₁₈H₁₈FN₃O
Molecular Weight:311.359
Hs Code.:

Synonyms:2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Suppliers and Price of 2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

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Technology Process of 2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

There total 4 articles about 2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 866133-65-5
2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid

: 75-64-9
tert-butylamine

: 1051397-27-3
2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Guidance literature:: With triethylamine; HATU; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

Reference yield:

: 36052-24-1
methyl 6-aminonicotinoate

: 1051397-27-3
2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1,4-dioxane / 8.5 h / Heating / reflux

2: hydrogen bromide / acetic acid / 10 h / 120 °C

3: triethylamine; HATU / N,N-dimethyl-formamide / 2 h / 20 °C

With hydrogen bromide; triethylamine; HATU; In 1,4-dioxane; acetic acid; N,N-dimethyl-formamide;

Reference yield:

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 1051397-27-3
2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridine-6-carboxylic acid tert-butylamide

Guidance literature:: Multi-step reaction with 3 steps

1: 1,4-dioxane / 8.5 h / Heating / reflux

2: hydrogen bromide / acetic acid / 10 h / 120 °C

3: triethylamine; HATU / N,N-dimethyl-formamide / 2 h / 20 °C

With hydrogen bromide; triethylamine; HATU; In 1,4-dioxane; acetic acid; N,N-dimethyl-formamide;