N,N-Dimethyl-2-phenylbutyramid

Base Information

• Chemical Name: N,N-Dimethyl-2-phenylbutyramid
• CAS No.: 33127-03-6
• Molecular Formula: C₁₂H₁₇NO
• Molecular Weight: 191.273
• Mol file: 33127-03-6.mol

Synonyms:N,N-Dimethyl-2-phenylbutyramid

Chemical Property of N,N-Dimethyl-2-phenylbutyramid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-Dimethyl-2-phenylbutyramid

There total 3 articles about N,N-Dimethyl-2-phenylbutyramid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N-dimethyl-2-phenylacetamide (18925-69-4) + ethyl iodide (75-03-6) → N,N-Dimethyl-2-phenylbutyramid (33127-03-6)

Guidance literature:

N,N-dimethyl-2-phenylacetamide; With n-butyllithium; diisopropylamine; lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.5h; Inert atmosphere;

ethyl iodide; In tetrahydrofuran; at 20 ℃; for 16h; Inert atmosphere;

DOI:10.1021/acs.orglett.6b02782

Reference yield:

2-Phenylbutyric acid (90-27-7) + dimethyl amine (124-40-3) → N,N-Dimethyl-2-phenylbutyramid (33127-03-6)

Guidance literature:

Reference yield:

→ N,N-Dimethyl-2-phenylbutyramid (33127-03-6)

Guidance literature:

Dimethylphenobarbital (II) durch Erhitzen m. Trimethylaniliniumhydroxid;

DOI:10.1002/jps.2600660430

upstream raw materials:

2-Phenylbutyric acid

dimethyl amine

N,N-dimethyl-2-phenylacetamide

ethyl iodide

Downstream raw materials:

(Z)-2-Phenyl-but-2-enoic acid dimethylamide

N,N-Dimethyl-2-phenyl-butylamin

2-Chloro-N,N-dimethyl-2-phenyl-butyramide

1-Chlor-2-phenyl-N,N-dimethylbutenylamin