Technology Process of 2,2-dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate
There total 8 articles about 2,2-dimethyl-4-oxo-3,8,11,14,17,20,23-heptaoxa-5-azapentacosan-25-yl 4-methylbenzenesulfonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
t-butyl 20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate;
With
triethylamine;
In
dichloromethane;
at 0 ℃;
for 0.0833333h;
p-toluenesulfonyl chloride;
In
dichloromethane;
at 0 - 20 ℃;
for 24h;
DOI:10.1002/ejoc.201001666
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: ethanol / 0 - 20 °C
2.1: dmap; triethylamine / dichloromethane / 20 °C / Inert atmosphere
3.1: sodium hydroxide / water; toluene / 1 h / 100 °C
3.2: 20 - 100 °C
4.1: triethylamine / dichloromethane / 0.08 h / 0 °C
4.2: 24 h / 0 - 20 °C
With
dmap; triethylamine; sodium hydroxide;
In
ethanol; dichloromethane; water; toluene;
DOI:10.1002/ejoc.201001666
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: palladium 10% on activated carbon; hydrogen / ethanol / 20 °C / 760.05 Torr
2.1: ethanol / 0 - 20 °C
3.1: dmap; triethylamine / dichloromethane / 20 °C / Inert atmosphere
4.1: sodium hydroxide / water; toluene / 1 h / 100 °C
4.2: 20 - 100 °C
5.1: triethylamine / dichloromethane / 0.08 h / 0 °C
5.2: 24 h / 0 - 20 °C
With
dmap; palladium 10% on activated carbon; hydrogen; triethylamine; sodium hydroxide;
In
ethanol; dichloromethane; water; toluene;
DOI:10.1002/ejoc.201001666
