Technology Process of C18H20ClNO4
There total 1 articles about C18H20ClNO4 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
4-chlorosalicylic acid; 2,2-dimethoxyethylamine;
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran;
for 2h;
benzyl bromide;
With
potassium carbonate;
In
ethyl acetate; N,N-dimethyl-formamide;
at 60 ℃;
for 2h;
- Guidance literature:
-
C18H20ClNO4;
With
hydrogenchloride;
In
tetrahydrofuran; water;
at 70 ℃;
for 2h;
With
hexachloroethane; triphenylphosphine;
In
acetonitrile;
for 0.5h;
With
pyridine;
In
acetonitrile;
at 20 - 60 ℃;
for 1.5h;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: hydrogenchloride / tetrahydrofuran; water / 2 h / 70 °C
1.2: 1.5 h / 20 - 60 °C
2.1: lead(IV) tetraacetate; butyldiadamantylphosphine; sodium t-butanolate / toluene / 15 h / 110 °C / Inert atmosphere
3.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 2 h
4.1: potassium carbonate; potassium iodide / N,N-dimethyl-formamide / 1 h / 90 °C
5.1: sodium hydroxide; water / N,N-dimethyl-formamide
With
hydrogenchloride; palladium 10% on activated carbon; butyldiadamantylphosphine; water; hydrogen; lead(IV) tetraacetate; potassium carbonate; potassium iodide; sodium hydroxide; sodium t-butanolate;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide; toluene;
