N-(3-bromophenyl)formamide

Base Information

• Chemical Name: N-(3-bromophenyl)formamide
• CAS No.: 37831-25-7
• Molecular Formula: C7H6 Br N O
• Molecular Weight: 200.035
• Hs Code.: 2924299090
• European Community (EC) Number: 636-444-2
• DSSTox Substance ID: DTXSID10558289
• Nikkaji Number: J149.392B
• Mol file: 37831-25-7.mol

Synonyms:3-Bromoformanilide;N-(3-bromophenyl)formamide;37831-25-7;meta-Bromoformanilide;n-(3-bromophenyl) formamide;SCHEMBL2089831;Formamide, N-(3-bromophenyl)-;DTXSID10558289;AKOS013153972

Chemical Property of N-(3-bromophenyl)formamide

Chemical Property:

• Vapor Pressure: 0.00012mmHg at 25°C
• Melting Point: 60-64 °C(lit.)
• Refractive Index: 1.633
• Boiling Point: 335.4°C at 760 mmHg
• Flash Point: 156.7°C
• PSA: 29.10000
• Density: 1.634g/cm³
• LogP: 2.72630
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 198.96328
• Heavy Atom Count: 10
• Complexity: 118

Purity/Quality:

99% ^*data from raw suppliers

3-BROMOFORMANILIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-36/38
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC(=C1)Br)NC=O

Technology Process of N-(3-bromophenyl)formamide

There total 17 articles about N-(3-bromophenyl)formamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

Methyl formate (107-31-3) + m-Bromoaniline (591-19-5) → N-(3-bromophenyl)formamide (37831-25-7)

Guidance literature:

With calcium(II) bis(trifluoromethanesulfonyl)imide; In neat (no solvent); at 115 ℃; for 1h; Temperature; Reagent/catalyst; Microwave irradiation; Sealed tube;

DOI:10.1002/ejoc.201600226

Reference yield: 97.0%

→ N-(3-bromophenyl)formamide (37831-25-7)

Guidance literature:

With nitromethane; calcium(II) bis(trifluoromethanesulfonyl)imide; at 115 ℃; for 1h; Microwave irradiation; Sealed tube;

Reference yield: 95.0%

formic acid (64-18-6) + m-Bromoaniline (591-19-5) → N-(3-bromophenyl)formamide (37831-25-7)

Guidance literature:

With aminopropylated mesoporous SBA-15 silica; at 40 ℃; for 0.0833333h; chemoselective reaction; Neat (no solvent);

DOI:10.1135/cccc2011131

upstream raw materials:

formic acid

m-Bromoaniline

trimethyl orthoformate

(3-bromophenyl)boronic acid

Downstream raw materials:

N-(3-bromophenyl)-2-phenylacetamide

m-Bromoaniline

N-(3-bromophenyl)-N-formyl-2-(thiophen-2-yl)acetamide

1-bromo-3-isocyanobenzene