N-cyclohexylisonicotinamide

Base Information

Chemical Name:N-cyclohexylisonicotinamide
CAS No.:10354-59-3
Molecular Formula:C₁₂H₁₆N₂O
Molecular Weight:204.272
Hs Code.:

Synonyms:N-cyclohexylisonicotinamide

Suppliers and Price of N-cyclohexylisonicotinamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-cyclohexylisonicotinamide

Chemical Property:

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Technology Process of N-cyclohexylisonicotinamide

There total 7 articles about N-cyclohexylisonicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 14254-57-0
4-(chlorocarbonyl)pyridine

: 108-91-8,157973-60-9
cyclohexylamine

: 10354-59-3
N-cyclohexylisonicotinamide

Guidance literature:: In dichloromethane; at 25 ℃; for 18h;

Reference yield: 85.0%

: 1570-45-2
isonicotinic acid ethylester

: 108-91-8,157973-60-9
cyclohexylamine

: 10354-59-3
N-cyclohexylisonicotinamide

Guidance literature:: With potassium tert-butylate; water; oxygen; In tetrahydrofuran; at 20 ℃; for 0.166667h;
DOI:10.1055/s-0031-1289622

Reference yield: 81.0%

: 1453-82-3
isonicotinamide

: 98-89-5
Cyclohexanecarboxylic acid

: 10354-59-3
N-cyclohexylisonicotinamide

Guidance literature:: With copper(I) thiophene-2-carboxylate; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(5-methyl-2-(4-fluorophenyl)pyridine(-1H))-iridium(III) hexafluorophosphate; N,N,N′,N′-tetramethyl-N″-tert-butylguanidine; bathophenanthroline; iodomesitylene diacetate; In 1,4-dioxane; at 20 ℃; for 1h; regioselective reaction; Inert atmosphere; Irradiation;
DOI:10.1038/s41586-018-0234-8