2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1)

Base Information

Chemical Name:2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1)
CAS No.:895521-36-5
Molecular Formula:C₄H₆O₅*C₁₁H₁₁F₆N
Molecular Weight:405.294
Hs Code.:
Mol file:895521-36-5.mol

Synonyms:[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl](methyl)amine L-malate

Suppliers and Price of 2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1) >95%
500mg
$ 486.00

Crysdot
(R)-1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine2-hydroxysuccinate 95+%
5g
$ 961.00

Crysdot
(R)-1-(3,5-Bis(trifluoromethyl)phenyl)-N-methylethanamine2-hydroxysuccinate 95+%
1g
$ 418.00

American Custom Chemicals Corporation
2-HYDROXYBUTANEDIOIC ACID, (1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-N-METHYLETHANAMINE (1:1) 95.00%
10G
$ 2482.67

American Custom Chemicals Corporation
2-HYDROXYBUTANEDIOIC ACID, (1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-N-METHYLETHANAMINE (1:1) 95.00%
5G
$ 1712.87

American Custom Chemicals Corporation
2-HYDROXYBUTANEDIOIC ACID, (1R)-1-[3,5-BIS(TRIFLUOROMETHYL)PHENYL]-N-METHYLETHANAMINE (1:1) 95.00%
1G
$ 962.35

Total 2 raw suppliers

Chemical Property of 2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1)

Chemical Property:

Melting Point:126-128°

Purity/Quality:

98%min ^*data from raw suppliers

2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1) >95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1)

There total 1 articles about 2-Hydroxybutanedioic acid - (1R)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 617-48-1,78644-42-5
malic acid

: 30071-93-3
3,5-bis(trifluoromethyl)phenyl methyl ketone

: 74-89-5
methylamine

: 895521-36-5
[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl](methyl)amine L-malate

Guidance literature:: 3,5-bis(trifluoromethyl)phenyl methyl ketone; methylamine; In methanol; ethanol; at 25 ℃; for 24.25h; Inert atmosphere;

With sodium tetrahydroborate; In methanol; ethanol; at 0 ℃; for 2h;

malic acid; In ethyl acetate; at 0 - 25 ℃; for 5h;

Reference yield:

: 895521-36-5
[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl](methyl)amine L-malate

: 334477-60-0
[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl](methyl)amine

Guidance literature:: With sodium hydroxide; In ethyl acetate;

Reference yield:

: 895521-36-5
[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl](methyl)amine L-malate

: 1453070-40-0
(1S,8aS)-dimethyl 2-(methyl((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethyl)carbamoyl)-6-oxo-1-o-tolylhexahydropyrrolo[1,2-a]pyrazine-7,7(6H)-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / ethyl acetate

2.1: triethylamine / ethyl acetate / 2 h / 0 °C

2.2: 39 h

3.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -60 °C / Inert atmosphere

3.2: 3 h / -60 - 20 °C

With triethylamine; sodium hydroxide; lithium hexamethyldisilazane; In tetrahydrofuran; ethyl acetate;