Technology Process of 1,4-Benzodioxin-5-carboxylicacid,2,3-dihydro-7-methyl-,methylester(9CI)
There total 7 articles about 1,4-Benzodioxin-5-carboxylicacid,2,3-dihydro-7-methyl-,methylester(9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
palladium diacetate; triethylamine;
In
N,N-dimethyl-formamide;
at 70 ℃;
for 52h;
under 760.051 Torr;
- Guidance literature:
-
With
potassium carbonate;
In
acetone;
for 24h;
Heating / reflux;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: caesium carbonate / N,N-dimethyl-formamide / 7.33 h / 100 °C
2.1: potassium carbonate / N,N-dimethyl-formamide / 0.08 h / 20 °C
2.2: 2.5 h / 20 °C
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.5 h / Cooling with ice
4.1: palladium(II) hydroxide; hydrogen; acetic acid / 16 h / 20 °C
5.1: pyridine / dichloromethane / 2.58 h / -78 - -25 °C
6.1: triethylamine; palladium diacetate / N,N-dimethyl-formamide / 52 h / 70 °C / 760.05 Torr
With
pyridine; lithium aluminium tetrahydride; hydrogen; palladium diacetate; palladium(II) hydroxide; potassium carbonate; caesium carbonate; acetic acid; triethylamine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;