4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Base Information

Chemical Name:4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde
CAS No.:1376514-17-8
Molecular Formula:C₂₀H₂₈N₄O₃
Molecular Weight:372.467
Hs Code.:

Synonyms:4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Suppliers and Price of 4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

There total 9 articles about 4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1376607-33-8
(3S)-3-({2-amino-5-[4-(hydroxymethyl)-2-methoxybenzyl]-6-methylpyrimidin-4-yl}amino)hexan-1-ol

: 1376514-17-8
4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Guidance literature:: With manganese(IV) oxide; In tetrahydrofuran; dichloromethane; at 20 ℃; for 3.83333h;

Reference yield:

: 1376514-16-7
4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzonitrile

: 1376514-17-8
4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Guidance literature:: With pyridine; sodium hypophosphite monohydrate; acetic acid; Raney nickel; In water; at 45 ℃; for 16h; Product distribution / selectivity;

Reference yield:

: 104436-60-4
4-bromomethyl-3-methoxybenzonitrile

: 1376514-17-8
4-[(2-amino-4-{[(3S)-1-hydroxyhexan-3-yl]amino}-6-methylpyrimidin-5-yl)methyl]-3-methoxybenzaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.33 h / 0 °C

1.2: 16 h / 70 °C

2.1: methanol / 16 h / 65 °C

3.1: trichlorophosphate / 16 h / 100 °C

3.2: 1 h / 50 °C / pH 7

4.1: 1,4-dioxane / 9 h / 180 °C / Microwave irradiation

5.1: pyridine; acetic acid; sodium hypophosphite monohydrate / Raney nickel / water / 16 h / 45 °C

With pyridine; sodium hypophosphite monohydrate; sodium hydride; acetic acid; trichlorophosphate; Raney nickel; In tetrahydrofuran; 1,4-dioxane; methanol; water; mineral oil;