N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine

Base Information

Chemical Name:N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine
CAS No.:88211-44-3
Molecular Formula:C8H23 N O Si2
Molecular Weight:205.448
Hs Code.:2931900090
DSSTox Substance ID:DTXSID80463351
Nikkaji Number:J1.202.876H
Wikidata:Q82288212
Mol file:88211-44-3.mol

Synonyms:88211-44-3;N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine;1-methoxy-N,N-bis(trimethylsilyl)methanamine;SCHEMBL4907600;DTXSID80463351;MFCD17018871;SY287544;N,N-bis(trimethylsilyl)aminomethyl methyl ether

Suppliers and Price of N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
AMINOMETHYLATING REAGENT A 95.00%
5MG
$ 496.50

Total 3 raw suppliers

Chemical Property of N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine

Chemical Property:

Boiling Point:73 °C(Press: 16 Torr)
PKA:11.16±0.70(Predicted)
PSA：12.47000
Density:0.836±0.06 g/cm3(Predicted)
LogP:2.56210
Solubility.:sol organic solvents such as hexane, dichloromethane, ether, alcohol; stable in neutral or basic solvents; unstable in protic solvents.
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:205.13181743
Heavy Atom Count:12
Complexity:123

Purity/Quality:: AMINOMETHYLATING REAGENT A 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COCN([Si](C)(C)C)[Si](C)(C)C
Physical properties bp 94–95 °C/83 mmHg; d 0.873 g cm?3; n20 D 1.431–1.434.
Uses (Methoxymethyl)bis(trimethylsilyl)amine is widely used as electrophilic N,N-bis(trimethylsilyl)aminomethylating agent for a variety of molecules; after desilylation, the overall transformation achieves primary aminomethylation.

Technology Process of N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine

There total 4 articles about N-(Methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 107-30-2
chloromethyl methyl ether

: 999-97-3
1,1,1,3,3,3-hexamethyl-disilazane

: 88211-44-3
N-(methoxymethyl)-1,1,1-trimethyl-N-(trimethylsilyl)silanamine

Guidance literature:: 1,1,1,3,3,3-hexamethyl-disilazane; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

chloromethyl methyl ether; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jacs.1c00249