4-Methoxy-1,2-dihydronaphthalene

Base Information

• Chemical Name: 4-Methoxy-1,2-dihydronaphthalene
• CAS No.: 84716-82-5
• Molecular Formula: C11H12 O
• Molecular Weight: 160.216
• Hs Code.: 2909309090
• DSSTox Substance ID: DTXSID40446726
• Wikidata: Q82265442
• Mol file: 84716-82-5.mol

Synonyms:4-methoxy-1,2-dihydronaphthalene;84716-82-5;1-Methoxy-3,4-dihydronaphthalene;SCHEMBL6161470;DTXSID40446726;SFYRKVZGSRDBSY-UHFFFAOYSA-N;AKOS006291362;AC-20822

Chemical Property of 4-Methoxy-1,2-dihydronaphthalene

Chemical Property:

• Vapor Pressure: 0.00999mmHg at 25°C
• Refractive Index: 1.559
• Boiling Point: 272.7°C at 760 mmHg
• Flash Point: 113.1°C
• PSA: 9.23000
• Density: 1.05g/cm³
• LogP: 2.62010
• XLogP3: 2.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 160.088815002
• Heavy Atom Count: 12
• Complexity: 183

Purity/Quality:

99% ^*data from raw suppliers

4-METHOXY-1,2-DIHYDRO-NAPHTHALENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CCCC2=CC=CC=C21

Technology Process of 4-Methoxy-1,2-dihydronaphthalene

There total 5 articles about 4-Methoxy-1,2-dihydronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

trimethyl phosphite (512-56-1) + 3,4-dihydronaphthalene-1(2H)-one (529-34-0) → 4-methoxy-1,2-dihydronaphthalene (84716-82-5)

Guidance literature:

With sodium hydride; In 1-methyl-pyrrolidin-2-one; at 120 ℃; for 24h;

DOI:10.1055/a-1504-8366

Reference yield:

3,4-dihydronaphthalene-1(2H)-one (529-34-0) + trimethyl orthoformate (149-73-5) → 4-methoxy-1,2-dihydronaphthalene (84716-82-5)

Guidance literature:

With toluene-4-sulfonic acid; for 24h; Ambient temperature;

Reference yield:

3,4-dihydronaphthalene-1(2H)-one (529-34-0) + trimethyl orthoformate (149-73-5) → 4-methoxy-1,2-dihydronaphthalene (84716-82-5) + 1,1-dimethoxy-1,2,3,4-tetrahydronaphthalene (105644-28-8)

Guidance literature:

With pyridinium p-toluenesulfonate; In methanol; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00111a058

upstream raw materials:

3,4-dihydronaphthalene-1(2H)-one

trimethyl orthoformate

2,2-dimethoxy-propane

trimethyl phosphite

Downstream raw materials:

2-bromo-1-tetralone

1-Methoxynaphthalene

2-hydroxy-1-tetralone

2-fluoro-1-tetralone