Dimethyl (2-fluoro-6-methoxyphenyl)boronate

Base Information

Chemical Name:Dimethyl (2-fluoro-6-methoxyphenyl)boronate
CAS No.:75626-21-0
Molecular Formula:C₉H₁₂BFO₃
Molecular Weight:198.002
Hs Code.:
DSSTox Substance ID:DTXSID00703701
Wikidata:Q82635939
Mol file:75626-21-0.mol

Synonyms:75626-21-0;Dimethyl (2-fluoro-6-methoxyphenyl)boronate;(2-fluoro-6-methoxyphenyl)-dimethoxyborane;2-FLUORO-6-METHOXYPHENYLBORONIC ACID DIMETHYL ESTER;starbld0016979;DTXSID00703701

Suppliers and Price of Dimethyl (2-fluoro-6-methoxyphenyl)boronate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Dimethyl (2-fluoro-6-methoxyphenyl)boronate

Chemical Property:

Boiling Point:241.7±30.0 °C(Predicted)
PSA：27.69000
Density:1.07±0.1 g/cm3(Predicted)
LogP:0.82230
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:198.0863526
Heavy Atom Count:14
Complexity:166

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=C(C=CC=C1F)OC)(OC)OC

Technology Process of Dimethyl (2-fluoro-6-methoxyphenyl)boronate

There total 3 articles about Dimethyl (2-fluoro-6-methoxyphenyl)boronate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 121-43-7,63156-11-6
Trimethyl borate

: 446-59-3
2‐bromo‐1‐fluoro‐3‐methoxybenzene

: 75626-21-0
C₉H₁₂BFO₃

Guidance literature:: 2‐bromo‐1‐fluoro‐3‐methoxybenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -75 ℃; for 0.5h;

Trimethyl borate; In tetrahydrofuran; hexane; at -75 ℃; for 0.0833333h;
DOI:10.1016/j.ejmech.2014.10.073

Reference yield:

: 121-43-7,63156-11-6
Trimethyl borate

: 75626-21-0
C₉H₁₂BFO₃

Guidance literature:: 2-MeO-6-F-C₆H₃-Br (or Cl); With n-butyllithium; In tetrahydrofuran; at -78 ℃;

Trimethyl borate; In tetrahydrofuran;
DOI:10.1016/S0960-894X(02)00460-2

Reference yield:

: 443-81-2
2-bromo-3-fluorophenol

: 75626-21-0
C₉H₁₂BFO₃

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 24 h / 20 °C

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -75 °C

2.2: 0.08 h / -75 °C

With n-butyllithium; potassium carbonate; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2014.10.073