N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone

Base Information

• Chemical Name: N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone
• CAS No.: 1430730-32-7
• Molecular Formula: C₄₂H₃₇N₃O₁₁S
• Molecular Weight: 791.835
• Mol file: 1430730-32-7.mol

Synonyms:N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone

Chemical Property of N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone

There total 2 articles about N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

ethyl C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formimidate (1430730-28-1) + toluene-4-sulfonic acid hydrazide (1576-35-8) → N1-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone (1430730-32-7)

Guidance literature:

In dichloromethane; at 20 ℃; for 72h;

DOI:10.1021/ml4001529

Reference yield:

2,6-anhydro-3,4,5,7-tetra-O-benzoyl-D-glycero-D-gulo-heptonamide (286369-06-0) → N1-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone (1430730-32-7)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane / 20 °C / Inert atmosphere

2: dichloromethane / 72 h / 20 °C

In dichloromethane;

Reference yield: 77.0%

N1-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone (1430730-32-7) + pivaloyl chloride (3282-30-2) → N4-(pivaloyl)-N1-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone (1430730-67-8)

Guidance literature:

With pyridine; dmap; In chloroform; at 20 ℃; Reflux;

upstream raw materials:

ethyl C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formimidate

toluene-4-sulfonic acid hydrazide

2,6-anhydro-3,4,5,7-tetra-O-benzoyl-D-glycero-D-gulo-heptonamide

Downstream raw materials:

3-methyl-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

3-(tert-butyl)-5-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)-1,2,4-triazole

5-methyl-3-(2',3',4',6'-tetra-O-benzoyl-β-D-glucopyranosyl)-1-tosyl-1,2,4-triazole

N⁴-(pivaloyl)-N¹-tosyl-C-(2,3,4,6-tetra-O-benzoyl-β-D-glucopyranosyl)formamidrazone