(Chloromethoxy)methoxymethane

Base Information

• Chemical Name: (Chloromethoxy)methoxymethane
• CAS No.: 122776-88-9
• Molecular Formula: C₃H₇ClO₂
• Molecular Weight: 110.54
• DSSTox Substance ID: DTXSID201307687
• Mol file: 122776-88-9.mol

Synonyms:122776-88-9;(Chloromethoxy)methoxymethane;Chloro(methoxymethoxy)methane;SCHEMBL10421248;DTXSID201307687;AKOS006384871;A936877

Chemical Property of (Chloromethoxy)methoxymethane

Chemical Property:

• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 110.0134572
• Heavy Atom Count: 6
• Complexity: 24.8

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COCOCCl

Technology Process of (Chloromethoxy)methoxymethane

There total 1 articles about (Chloromethoxy)methoxymethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloromethyl methyl ether (107-30-2) → methanol (67-56-1) + methylene chloride (74-87-3) + Methyl formate (107-31-3) + (methoxymethoxy)methyl chloride (122776-88-9)

Guidance literature:

With zinc(II) chloride; for 50h; Further Variations:; other periods of time; Product distribution;

Reference yield: 99.0%

dimethyl 4-bromo-5-hydroxy-benzene-1,3-dicarboxylate + (methoxymethoxy)methyl chloride (122776-88-9) → dimethyl 4-bromo-5-(methoxymethoxy)isophthalate

Guidance literature:

With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 0.666667h;

DOI:10.1016/j.tetlet.2015.06.075

Reference yield: 89.0%

4-Bromoresorcinol (6626-15-9) + (methoxymethoxy)methyl chloride (122776-88-9) → 1-bromo-2,4-bis(methoxymethoxy)benzene (295788-93-1)

Guidance literature:

4-Bromoresorcinol; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

(methoxymethoxy)methyl chloride; With tetra-(n-butyl)ammonium iodide; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 2h;

DOI:10.1016/j.tetlet.2015.06.075

upstream raw materials:

chloromethyl methyl ether

Downstream raw materials:

(1S,5R,3Z)-3,5-dimethyl-6-(methoxymethoxy)-1-phenylhex-3-en-1-ol

(+/-)-(1-(methoxymethoxy)but-3-en-1-yl)benzene

1-bromo-2,4-bis(methoxymethoxy)benzene