benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester

Base Information

• Chemical Name: benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester
• CAS No.: 216104-33-5
• Molecular Formula: C₂₅H₃₂ClNO₃
• Molecular Weight: 429.987
• Mol file: 216104-33-5.mol

Synonyms:benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester

Chemical Property of benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester

There total 1 articles about benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 10.1%

2,2,6,6-Tetramethyl-1-piperidinyloxy free radical (2564-83-2,45842-10-2,126517-51-9,25657-03-8,26933-82-4,54637-06-8,64104-42-3) + 4-Vinylbenzyl chloride (1592-20-7,29296-32-0) + dibenzoyl peroxide (94-36-0) → benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester (216104-33-5)

Guidance literature:

at 80 ℃;

DOI:10.1021/ma035285p

Reference yield: 79.0%

allylmagnesium bromide (2622-05-1) + benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester (216104-33-5) → 2-[4-(but-3-enyl)phenyl]-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)ethanol (852837-09-3)

Guidance literature:

In tetrahydrofuran; at 60 ℃; for 2h;

DOI:10.1021/ja0422561

Reference yield: 76.8%

2-(tetrahydropyran-2-yloxy)ethanol (2162-31-4) + benzoic acid 2-(4-chloromethyl-phenyl)-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethyl ester (216104-33-5) → 2-{4-[2-(tetrahydro-pyran-2-yloxy)-ethoxymethyl]-phenyl}-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethanol (697248-56-9)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/ma036010c

upstream raw materials:

2,2,6,6-Tetramethyl-1-piperidinyloxy free radical

4-Vinylbenzyl chloride

dibenzoyl peroxide

Downstream raw materials:

2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-2-(4-undec-10-enyloxymethyl-phenyl)-ethanol

2-[4-(but-3-enyl)phenyl]-2-(2,2,6,6-tetramethylpiperidin-1-yloxy)ethanol

2-{4-[2-(tetrahydro-pyran-2-yloxy)-ethoxymethyl]-phenyl}-2-(2,2,6,6-tetramethyl-piperidin-1-yloxy)-ethanol

2-[4-(2-oxa-4-hydroxybutyl)phenyl]-1-(2,2,6,6,-tetramethyl-1-piperidinyloxy)ethyl 2-bromo-2-methylpropionate