4-(4-Fluorophenyl)-1H-imidazole

Base Information

Chemical Name:4-(4-Fluorophenyl)-1H-imidazole
CAS No.:65020-70-4
Molecular Formula:C9H7 F N2
Molecular Weight:162.166
Hs Code.:2933290090
European Community (EC) Number:626-219-7
DSSTox Substance ID:DTXSID40349703
Nikkaji Number:J2.634.421B
Wikidata:Q27454107
ChEMBL ID:CHEMBL457835
Mol file:65020-70-4.mol

Synonyms:4-(4-Fluorophenyl)-1H-imidazole;65020-70-4;5-(4-fluorophenyl)-1H-imidazole;4-(4-fluoro-phenyl)-1H-imidazole;5-(4-Fluorophenyl)-3H-imidazole;SMR000038796;1H-IMIDAZOLE, 5-(4-FLUOROPHENYL)-;MLS000071196;SCHEMBL464496;CHEMBL457835;REGID_for_CID_657876;BDBM24671;DTXSID40349703;QYDAFWKRBZYBOB-UHFFFAOYSA-N;HMS2273C18;MFCD00297041;STL190853;AKOS001124632;4-(4-fluorophenyl)-1H-imidazole, 9;FS-4434;NCGC00018566-01;NCGC00018566-02;NCGC00018566-03;4-(4-Fluorophenyl)-1H-imidazole, 97%;CS-0454541;EN300-18903;P16444;Q27454107;Z94601534;3SQ

Suppliers and Price of 4-(4-Fluorophenyl)-1H-imidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(4-Fluorophenyl)-1h-imidazole
100mg
$ 45.00

TRC
4-(4-Fluorophenyl)-1h-imidazole
500mg
$ 65.00

SynQuest Laboratories
4-(4-Fluorophenyl)-1H-imidazole 98%
10 g
$ 208.00

SynQuest Laboratories
4-(4-Fluorophenyl)-1H-imidazole 98%
25 g
$ 400.00

Sigma-Aldrich
4-(4-Fluorophenyl)-1H-imidazole 97%
5g
$ 328.00

Heterocyclics
4-(4-Fluorophenyl)-1H-imidazole 97%
5g
$ 59.00

Heterocyclics
4-(4-Fluorophenyl)-1H-imidazole 97%
25g
$ 216.00

Crysdot
4-(4-Fluorophenyl)-1H-imidazole 97%
100g
$ 790.00

Apolloscientific
4-(4-Fluorophenyl)-1H-imidazole 98%
25g
$ 250.00

Apolloscientific
4-(4-Fluorophenyl)-1H-imidazole 98%
10g
$ 130.00

Total 13 raw suppliers

Chemical Property of 4-(4-Fluorophenyl)-1H-imidazole

Chemical Property:

Melting Point:124-129 °C
PSA：28.68000
LogP:2.21580
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:162.05932639
Heavy Atom Count:12
Complexity:144

Purity/Quality:

99% ^*data from raw suppliers

4-(4-Fluorophenyl)-1h-imidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-41
Safety Statements: 26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CN=CN2)F

Technology Process of 4-(4-Fluorophenyl)-1H-imidazole

There total 3 articles about 4-(4-Fluorophenyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 77287-34-4,77287-35-5,60100-09-6
formamide

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 65020-70-4
4-(4-fluorophenyl)-1H-imidazole

Guidance literature:: at 170 - 180 ℃; Inert atmosphere;
DOI:10.1021/jm800512z

Reference yield:

: 144-55-8
sodium hydrogencarbonate

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 65020-70-4
4-(4-fluorophenyl)-1H-imidazole

Guidance literature:: With formamide; In ethyl acetate;

Reference yield:

: 766-98-3
1-ethynyl-4-fluorobenzene

: 65020-70-4
4-(4-fluorophenyl)-1H-imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: dodecacarbonyl-triangulo-triruthenium / toluene / 2 h / 100 °C / Inert atmosphere

2: ammonium carbonate / 6 h / 64 °C

With dodecacarbonyl-triangulo-triruthenium; ammonium carbonate; In toluene;
DOI:10.1055/s-0037-1611871