1-HEXYLZINC BROMIDE

Base Information

• Chemical Name: 1-HEXYLZINC BROMIDE
• CAS No.: 124397-96-2
• Molecular Formula: C6H13 Br Zn
• Molecular Weight: 230.463
• Mol file: 124397-96-2.mol

Synonyms:Hexane,zinc complex; (Hexan-1-yl)zinc bromide; 1-Hexylzinc bromide; Hexylzinc bromide

Chemical Property of 1-HEXYLZINC BROMIDE

Chemical Property:

• Vapor Pressure: 151mmHg at 25°C
• Refractive Index: ">
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 0.00000
• Density: g/cm³
• LogP: 3.37740
• Storage Temp.: 2-8°C
• Sensitive.: Air Sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

Hexylzinc bromide solution 0.5 M in THF ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xn
• Statements: 19-22-36/38-40-36/37-14-11
• Safety Statements: 16-26-33-36-36/37

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-HEXYLZINC BROMIDE

There total 5 articles about 1-HEXYLZINC BROMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-bromo-hexane (111-25-1) + zinc (7440-66-6) → (1-hexyl)zinc(II) bromide (124397-96-2)

Guidance literature:

zinc; With iodine; In N,N-dimethyl acetamide; at 20 ℃; for 0.166667h;

1-bromo-hexane; In N,N-dimethyl acetamide; at 80 ℃; for 3h;

DOI:10.1021/jm301304e

Reference yield:

1-bromo-hexane (111-25-1) + ethylene dibromide (106-93-4) + zinc (7440-66-6) → (1-hexyl)zinc(II) bromide (124397-96-2)

Guidance literature:

zinc; With lithium chloride; at 160 ℃; for 0.333333h; Inert atmosphere;

1-bromo-hexane; ethylene dibromide; With chloro-trimethyl-silane; iodine; In tetrahydrofuran; at 50 ℃; for 16h; Inert atmosphere;

DOI:10.1016/j.bmcl.2020.127293

Reference yield:

1-bromo-hexane (111-25-1) → (1-hexyl)zinc(II) bromide (124397-96-2)

Guidance literature:

With Zn#Cu; In further solvent(s); addn. of alkyl bromide in ethyl carbonate to Zn-Cu; heated to 95°C (3-4 h);

DOI:10.1016/0022-328X(89)87244-4

upstream raw materials:

di(n-hexyl)zinc

zinc dibromide

1-bromo-hexane

zinc

Downstream raw materials:

octane

dodecane

2,5-dibromo-3-hexylthiophene

3-hexylthiophene

Refernces

• 1、 Kato, Atsushi,Nakagome, Izumi,Sato, Kasumi,Yamamoto, Arisa,Adachi, Isao,Nash, Robert J.,Fleet, George W. J.,Natori, Yoshihiro,Watanabe, Yasuka,Imahori, Tatsushi,Yoshimura, Yuichi,Takahata, Hiroki,Hirono, Shuichi. "Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease". . p. 1039 - 1048. Retrieved 2016.
• 2、 Kranidiotis-Hisatomi, Nektarios,Oestreich, Martin,Yi, Hong. "Enantio- and Regioconvergent Nickel-Catalyzed C(sp3)?C(sp3) Cross-Coupling of Allylic Electrophiles Steered by a Silyl Group". . p. 13652 - 13655. Retrieved 2021.
• 3、 Fulton, Tyler J.,Alley, Phebe L.,Rensch, Heather R.,Ackerman, Adriana M.,Berlin, Cameron B.,Krout, Michael R.. "Access to Functionalized Quaternary Stereocenters via the Copper-Catalyzed Conjugate Addition of Monoorganozinc Bromide Reagents Enabled by N, N-Dimethylacetamide". . p. 14723 - 14732. Retrieved 2018/11/23.