DIPHENYLPHOSPHINIC ANHYDRIDE

Base Information

• Chemical Name: DIPHENYLPHOSPHINIC ANHYDRIDE
• CAS No.: 5849-36-5
• Molecular Formula: C24H20O3P2
• Molecular Weight: 418.369
• Mol file: 5849-36-5.mol

Synonyms:DIPHENYLPHOSPHINIC ANHYDRIDE

Chemical Property of DIPHENYLPHOSPHINIC ANHYDRIDE

Chemical Property:

• Vapor Pressure: 8.41E-12mmHg at 25°C
• Melting Point: 146 °C
• Refractive Index: 1.629
• Boiling Point: 555.3°C at 760 mmHg
• Flash Point: 302.5°C
• PSA: 62.99000
• Density: 1.28g/cm³
• LogP: 4.86120

Purity/Quality:

98%,99%, ^*data from raw suppliers

Diphenylphosphinic Anhydride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIPHENYLPHOSPHINIC ANHYDRIDE

There total 25 articles about DIPHENYLPHOSPHINIC ANHYDRIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

oxalyl dichloride (79-37-8) + sodium diphenylphosphinate (22214-04-6) → diphenylphosphinic anhydride (5849-36-5)

Guidance literature:

In diethyl ether;

Reference yield: 92.0%

Diphenylphosphinic chloride (1499-21-4) → diphenylphosphinic anhydride (5849-36-5)

Guidance literature:

With phenylphosphinic acid; sodium hydride; In tetrahydrofuran; at 20 ℃; chemoselective reaction; Inert atmosphere;

Reference yield: 70.0%

Diphenylphosphinic chloride (1499-21-4) → chloro-trimethyl-silane (75-77-4) + triiododiphenylphosphorane (59357-76-5) + diphenylphosphinic anhydride (5849-36-5)

Guidance literature:

With trimethylsilyl iodide; In 1,2-dichloro-ethane; at 100 ℃; for 10h;

upstream raw materials:

1,1,2,2-tetraphenyldiphosphane-1,2-dioxide

Diphenylphosphinic chloride

oxirane

iodo-diphenyl-phosphine

Downstream raw materials:

diphenylphosphinic fluoride

(R)-1,1'-Bi-2-naphthol

(S)-[1,1']-binaphthalenyl-2,2'-diol

(bis(diphenylphosphonic)anhydride) tin dibromide

Refernces

• 1、 Chen, Yuan,Fang, Siqiang,Pan, Jianke,Ren, Xiaoyu,Tan, Jian-Ping,Wang, Tianli,Zhang, Hongkui. "Enantiodivergent Kinetic Resolution of 1,1′-Biaryl-2,2′-Diols and Amino Alcohols by Dipeptide-Phosphonium Salt Catalysis Inspired by the Atherton–Todd Reaction". supporting information. p. 14921 - 14930. Retrieved 2021/05/10.
• 2、 Nycz. "New aspects connected with the synthesis of H-phosphinate anhydrides". experimental part. p. 589 - 594. Retrieved 2009/12/26.