N,N,3-triphenylprop-2-enamide

Base Information

• Chemical Name: N,N,3-triphenylprop-2-enamide
• CAS No.: 50395-70-5
• Molecular Formula: C21H17NO
• Molecular Weight: 299.372
• Hs Code.: 2924299090
• DSSTox Substance ID: DTXSID80377808
• Mol file: 50395-70-5.mol

Synonyms:N,N,3-triphenylprop-2-enamide;N,N-Diphenylcinnamamide;50395-70-5;N,N-diphenylstyrenyl carboxamide;DTXSID80377808;GCTCULHQKVKNJT-UHFFFAOYSA-N;MFCD00091271;AKOS005257014

Chemical Property of N,N,3-triphenylprop-2-enamide

Chemical Property:

• Vapor Pressure: 5.9E-09mmHg at 25°C
• Refractive Index: 1.67
• Boiling Point: 468.6°C at 760 mmHg
• Flash Point: 217.5°C
• PSA: 20.31000
• Density: 1.167g/cm³
• LogP: 5.06470
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 299.131014166
• Heavy Atom Count: 23
• Complexity: 367

Purity/Quality:

99% ^*data from raw suppliers

N,N-DIPHENYL CINNAMAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC(=O)N(C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of N,N,3-triphenylprop-2-enamide

There total 10 articles about N,N,3-triphenylprop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

cinnamoyl chloride (102-92-1,17082-09-6) + diphenylamine (122-39-4) → N,N-diphenylcinnamamide (50395-70-5)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 60 ℃;

DOI:10.1039/b926560k

Reference yield: 72.0%

N,N-diphenylacetamide (519-87-9) + benzaldehyde (100-52-7) → N,N-diphenylcinnamamide (50395-70-5)

Guidance literature:

With sodium hydroxide; In ethanol; Heating;

DOI:10.1016/j.ejmech.2003.09.009

Reference yield: 62.0%

carbon dioxide (124-38-9,18923-20-1) + N,N-diphenyl acrylamide (25574-93-0) + methyl iodide (74-88-4) + phenylboronic acid (98-80-6) → N,N-diphenylcinnamamide (50395-70-5) + C21H19NO + methyl 2-benzyl-3-(diphenylamino)-3-oxopropanoate

Guidance literature:

carbon dioxide; N,N-diphenyl acrylamide; phenylboronic acid; With chloro(1,5-cyclooctadiene)rhodium(I) dimer; N,N,N',N'',N'''-pentamethyldiethylenetriamine; silver trifluoromethanesulfonate; caesium carbonate; In N,N-dimethyl acetamide; at 60 ℃; for 24h; Sealed tube; Green chemistry;

methyl iodide; With potassium carbonate; In N,N-dimethyl acetamide; at 60 ℃; for 2h; regioselective reaction; Green chemistry;

DOI:10.1039/d0gc02667k

upstream raw materials:

cinnamoyl chloride

diphenylamine

Cinnamic acid

diphenylcarbamic chloride

Downstream raw materials:

3,4-diphenyl-adipic acid bis-diphenylamide

diphenyl-(6-phenyl-6,7-dihydro-5-oxa-9-aza-benzocyclohepten-8-yl)-amine

2-benzhydryl-3-oxo-N,3-diphenylpropanamide

(E)-3-benzylidene-1-phenylindolin-2-one