Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate

Base Information

Chemical Name:Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate
CAS No.:638128-20-8
Molecular Formula:C15H20N4O4
Molecular Weight:320.34
Hs Code.:
DSSTox Substance ID:DTXSID50700886
Mol file:638128-20-8.mol

Synonyms:638128-20-8;Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate;DTXSID50700886;Di-tert.-butyl 4-azido-2,6-pyridinedicarboxylate;J-400924

Suppliers and Price of Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DI-TERT-BUTYL-4-AZIDO-2,6-PYRIDINEDICARBOXYLATE 95.00%
5MG
$ 497.78

Total 1 raw suppliers

Chemical Property of Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate

Chemical Property:

PSA：115.24000
LogP:3.38676
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:7
Exact Mass:320.14845513
Heavy Atom Count:23
Complexity:465

Purity/Quality:: DI-TERT-BUTYL-4-AZIDO-2,6-PYRIDINEDICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C1=CC(=CC(=N1)C(=O)OC(C)(C)C)N=[N+]=[N-]

Technology Process of Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate

There total 3 articles about Di-tert-butyl 4-azidopyridine-2,6-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 638128-19-5
di-tert-butyl 4-chloropyridine-2,6-dicarboxylate

: 638128-20-8
tert-butoxy 4-azidopyridine-2,6-dicarboxylate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 50 ℃; for 24h;
DOI:10.1021/ja037895a

Reference yield:

: 71022-75-8
4-chloropyridine-2,6-dicarbonyl dichloride

: 638128-20-8
tert-butoxy 4-azidopyridine-2,6-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.79 g / 4-dimethylaminopyridine; pyridine / CH₂Cl₂ / 16 h / 20 °C

2: 97 percent / NaN₃ / dimethylformamide / 24 h / 50 °C

With pyridine; dmap; sodium azide; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja037895a

Reference yield:

: 138-60-3
chelidamic acid

: 638128-20-8
tert-butoxy 4-azidopyridine-2,6-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃ / 12 h / 128 °C

2: 1.79 g / 4-dimethylaminopyridine; pyridine / CH₂Cl₂ / 16 h / 20 °C

3: 97 percent / NaN₃ / dimethylformamide / 24 h / 50 °C

With pyridine; dmap; sodium azide; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja037895a