Valsartan benzyl ester

Base Information Edit

Chemical Name:Valsartan benzyl ester
CAS No.:137863-20-8
Molecular Formula:C31H35N5O3
Molecular Weight:525.651
Hs Code.:2933997500
European Community (EC) Number:604-047-3
UNII:2P0MPU907C
DSSTox Substance ID:DTXSID70160342
Nikkaji Number:J1.195.519C
Wikidata:Q27255284
Mol file:137863-20-8.mol

Synonyms:137863-20-8;Valsartan benzyl ester;(S)-benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate;2P0MPU907C;benzyl N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-N-pentanoyl-L-valinate;L-Valine, N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-, phenylmethyl ester;[(S-N-VALERYL-N-([2'-(1H-TETRAZOLE-5-YL)BIPHEN-4-YL]METHYL)-VALINE BENZYL ESTER);Benzyl (2S)-3-methyl-2-(pentanoyl((2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl)amino)butanoate;L-Valine, N-(1-oxopentyl)-N-((2'-(2H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, phenylmethyl ester;Benzyl (2S)-3-Methyl-2-[pentanoyl[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoate;Valsartan impurity B [EP];UNII-2P0MPU907C;Valsartan impurity B;EC 604-047-3;SCHEMBL2691;Benzyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate;DTXSID70160342;VXKKFWDUSKMRNO-LJAQVGFWSA-N;C31H35N5O3;SC1410;AKOS015854417;AKOS015899738;1894176-44-3;AS-78678;Benzyl (2S)-3-methyl-2-(N-((4-(2-(1H-1,2,3,4-tetrazol-5-yl)phenyl)phenyl)methyl)pentanamido)butanoate;VALSARTAN IMPURITY B [EP IMPURITY];A886381;Q27255284;[N-Valeryl-N[[2?-(1H-tetrazole-5-yl)biphenyl-4-yl]methyl]-L-valine Benzyl Ester;N-[(2'-(1H-tetrazol-5-yl)biphenyl-4-yl)methyl]-N-valeryl-(L)-valine benzyl ester;(S)-benzyl2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate;(S)-N-(1-benzyloxycarbonyl-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amine;(S)-N-(1-benzyloxycarbonyl-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)bi-phenyl-4-ylmethyl]-amine;(S)-N-(1-Benzyloxycarbonyl-2-methyl-prop-1-yl)-N-pentanoyl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-amine;BENZYL (2S)-3-METHYL-2-(N-{[2'-(1H-1,2,3,4-TETRAZOL-5-YL)-[1,1'-BIPHENYL]-4-YL]METHYL}PENTANAMIDO)BUTANOATE;benzyl (2S)-3-methyl-2-[N-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)pentanamido]butanoate;benzyl (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoate;L-Valine,N-(1-oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-,phenylmethyl ester;N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-L-valine Phenylmethyl Ester;Valsartan Imp. B (EP);Valsartan USP Related Compound C;Valsartan USP RC C;Benzyl (2S)-3-Methyl-2-[pentanoyl-[[2'-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl]amino]butanoate, Valsartan Imp B (EP), Valsartan Related Compound C (USP);Valsartan Related Compound C;Valsartan Impurity B

Suppliers and Price of Valsartan benzyl ester

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
ValsartanBenzylEster
10mg
$ 160.00

Sigma-Aldrich
Valsartan Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material
30mg
$ 511.00

Sigma-Aldrich
Valsartan Related Compound C United States Pharmacopeia (USP) Reference Standard
10mg
$ 1610.00

Matrix Scientific
(S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate 95+%
1g
$ 1557.00

Matrix Scientific
(S)-Benzyl 2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate 95+%
250mg
$ 722.00

Crysdot
(S)-Benzyl2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate 95+%
10mg
$ 295.00

Crysdot
(S)-Benzyl2-(N-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)pentanamido)-3-methylbutanoate 95+%
25mg
$ 405.00

Biosynth Carbosynth
N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]
100 mg
$ 400.00

Biosynth Carbosynth
N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]
50 mg
$ 300.00

Biosynth Carbosynth
N-(1-Oxopentyl)-N-[[2'-(2H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]
25 mg
$ 200.00

Total 92 raw suppliers

Chemical Property of Valsartan benzyl ester Edit

Chemical Property:

Vapor Pressure:0-0Pa at 20-25℃
Boiling Point:720.1 °C at 760 mmHg
PKA:4.15±0.10(Predicted)
Flash Point:389.3 °C
PSA：101.07000
Density:1.18 g/cm³
LogP:5.82050
Storage Temp.:Sealed in dry,Room Temperature
Solubility.:Chloroform (Slightly), Methanol (Slightly)
XLogP3:6.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:13
Exact Mass:525.27399000
Heavy Atom Count:39
Complexity:751

Purity/Quality:

99.9% ^*data from raw suppliers

ValsartanBenzylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)C(C(C)C)C(=O)OCC4=CC=CC=C4
Isomeric SMILES:CCCCC(=O)N(CC1=CC=C(C=C1)C2=CC=CC=C2C3=NNN=N3)[C@@H](C(C)C)C(=O)OCC4=CC=CC=C4
Uses Valsartan (V095750) intermediate. Valsartan (V095750) intermediate. Valsartan USP Related Compound C.

Technology Process of Valsartan benzyl ester

There total 22 articles about Valsartan benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%