1-(Trimethylsilyl)-1H-benzotriazole

Base Information

• Chemical Name: 1-(Trimethylsilyl)-1H-benzotriazole
• CAS No.: 43183-36-4
• Molecular Formula: C9H13N3Si
• Molecular Weight: 191.308
• Hs Code.: 2933990090
• European Community (EC) Number: 627-604-2
• Nikkaji Number: J637.586C
• Mol file: 43183-36-4.mol

Synonyms:1-(Trimethylsilyl)-1H-benzotriazole;43183-36-4;1-(Trimethylsilyl)-1H-benzo[d][1,2,3]triazole;48183-36-4;benzotriazol-1-yl(trimethyl)silane;1-trimethylsilylbenzotriazole;1-Trimethylsilyl-1H-benzotriazole;1-(trimethylsilyl)-1H-1,2,3-benzotriazole;1-TMS-1H-benzotriazole;N-trimethylsilylbenzotriazole;SCHEMBL1077517;MFCD00216577;1H-Benzotriazole,1-(trimethylsilyl)-;AKOS015840165;4'-(4-Ethylphenyl)bicyclohexyl-4-one;CS-W010721;AS-11268;1-(Trimethylsilyl)-1H-benzotriazole, 96%;T1752;D92518

Chemical Property of 1-(Trimethylsilyl)-1H-benzotriazole

Chemical Property:

• Vapor Pressure: 0.0209mmHg at 25°C
• Refractive Index: n20/D 1.545(lit.)
• Boiling Point: 251 °C at 760 mmHg
• PKA: 1.40±0.30(Predicted)
• Flash Point: 105.6 °C
• PSA: 30.71000
• Density: 1.07 g/cm³
• LogP: 2.11430
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 191.087873962
• Heavy Atom Count: 13
• Complexity: 190

Purity/Quality:

99% ^*data from raw suppliers

1-(Trimethylsilyl)-1H-benzotriazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F, Xi
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C[Si](C)(C)N1C2=CC=CC=C2N=N1

Technology Process of 1-(Trimethylsilyl)-1H-benzotriazole

There total 5 articles about 1-(Trimethylsilyl)-1H-benzotriazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.7%

1,2,3-Benzotriazole (95-14-7,27556-51-0) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → 1-(trimethylsilyl)-1H-benzotriazole (43183-36-4)

Guidance literature:

With sulfuric acid; heating, few hours;

Reference yield:

1,2,3-Benzotriazole (95-14-7,27556-51-0) + N,O-bis-(trimethylsilyl)-acetamide (10416-59-8) → 1-(trimethylsilyl)-1H-benzotriazole (43183-36-4)

Guidance literature:

at 130 ℃; for 1h;

DOI:10.1021/jo701608p

Reference yield:

benzoimidazole (51-17-2,79351-71-6) + chloro-trimethyl-silane (75-77-4) → 1-(trimethylsilyl)-1H-benzotriazole (43183-36-4)

Guidance literature:

With 1,1,1,3,3,3-hexamethyl-disilazane; for 2h; Heating;

DOI:10.1007/BF00473325

upstream raw materials:

benzoimidazole

chloro-trimethyl-silane

1,2,3-Benzotriazole

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

N-allylbenzotriazole

1,1′-carbonylbis-benzotriazole

(E)-3-Benzotriazol-2-yl-1-phenyl-propenone

1-cyanobenzotriazole

Refernces

• 1、 Boto, Alicia,Hernandez, Dacil,Hernandez, Rosendo,Alvarez, Eleuterio. "One-pot synthesis of acyclic nucleosides from carbohydrate derivatives, by combination of tandem and sequential reactions". . p. 9523 - 9532. Retrieved 2008/03/28.
• 2、 Yavorskii, A. E.,Stetsenko, A. V.,Zavgorodnii, S. G.,Florent'ev, V. L.. "Acyclic Analogs of Nucleosides. Synthesis of Hydroxyalkylbenzimidazoles and -Benzotriazoles". . p. 163 - 167. Retrieved 2007/10/02.