Tert-butyl(2-iodoethoxy)dimethylsilane

Base Information

• Chemical Name: Tert-butyl(2-iodoethoxy)dimethylsilane
• CAS No.: 101166-65-8
• Molecular Formula: C8H19IOSi
• Molecular Weight: 286.228
• European Community (EC) Number: 835-817-9
• DSSTox Substance ID: DTXSID80456329
• Nikkaji Number: J428.958G
• Wikidata: Q72503454
• Mol file: 101166-65-8.mol

Synonyms:TERT-BUTYL(2-IODOETHOXY)DIMETHYLSILANE;101166-65-8;tert-Butyl-(2-iodoethoxy)-dimethylsilane;1-(tert-Butyldimethylsilyloxy)-2-iodoethane;tert-butyl-(2-iodo-ethoxy)-dimethyl-silane;Silane, (1,1-dimethylethyl)(2-iodoethoxy)dimethyl-;MFCD09909940;C8H19IOSi;tert-butyl-(2-iodoethoxy)-dimethyl-silane;I(CH2)2OTBS;SCHEMBL740880;DTXSID80456329;CAAUZMMMFDVBFD-UHFFFAOYSA-N;BCP22835;BEA16665;t-butyl(2-iodoethoxy)dimethylsilane;t-butyl (2-iodoethoxy)dimethylsilane;1-t-butyldimethylsilyloxy-2-iodoethane;AKOS015837832;t-butyl-(2-iodoethyloxy)dimethylsilane;AM85442;CS-W006048;PB39384;(2-iodoethoxy)-tert-butyldimethylsilane;2-(t-butyldimethylsilyloxy)ethyl iodide;2-(t-butyldimethylsilyloxy) ethyl iodide;1-iodo-2-(t-butyldimethylsilyloxy)ethane;AS-20025;SY105664;1-(tert-Butyldimethylsiloxy)-2-iodoethane;tertiary-butyl (2-iodoethoxy)dimethylsilane;B5885;FT-0713874;EN300-268698;(1,1-dimethylethyl)(2-iodoethoxy)dimethylsilane;A897224;F9994-5425

Chemical Property of Tert-butyl(2-iodoethoxy)dimethylsilane

Chemical Property:

• Vapor Pressure: 0.288mmHg at 25°C
• Refractive Index: 1.476
• Boiling Point: 209.794 °C at 760 mmHg
• Flash Point: 80.681 °C
• PSA: 9.23000
• Density: 1.292 g/cm³
• LogP: 3.44320
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 286.02499
• Heavy Atom Count: 11
• Complexity: 118

Purity/Quality:

97% ^*data from raw suppliers

tert-butyl(2-iodoethoxy)dimethylsilane 97+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OCCI

Technology Process of Tert-butyl(2-iodoethoxy)dimethylsilane

There total 10 articles about Tert-butyl(2-iodoethoxy)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl (2-chloroethoxy)dimethyl silane (89031-81-2) → 2-tert-butyldimethylsilyloxyethyl iodide (101166-65-8)

Guidance literature:

With sodium iodide; In acetone; at 120 ℃; for 4h; Inert atmosphere; Sealed tube; Microwave irradiation;

DOI:10.1016/j.tet.2014.06.090

Reference yield: 99.0%

Iodoethanol (624-76-0) + tert-butyldimethylsilyl chloride (18162-48-6) → 2-tert-butyldimethylsilyloxyethyl iodide (101166-65-8)

Guidance literature:

With 1H-imidazole; In dichloromethane; at 0 - 23 ℃; for 2.5h; Inert atmosphere;

DOI:10.1002/chem.201605029

Reference yield: 98.0%

1H-imidazole (288-32-4) + Iodoethanol (624-76-0) + tert-butyldimethylsilyl chloride (18162-48-6) → 2-tert-butyldimethylsilyloxyethyl iodide (101166-65-8)

Guidance literature:

In dichloromethane;

upstream raw materials:

oxirane

tert-butyldimethylsilyl chloride

tert-butyl (2-chloroethoxy)dimethyl silane

ethyl iodide

Downstream raw materials:

1-t-Butyldimethylsilyloxy-3,3-bis(phenylsulphonyl)propane

1-<(tert-butyldimethylsilyl)oxy>-3-<(4-chlorophenyl)thio>-5-methylhexa-3,4-diene

tert-Butyl-dimethyl-(2-{2-[(E)-2-(2,6,6-trimethyl-cyclohex-1-enyl)-vinyl]-[1,3]dithian-2-yl}-ethoxy)-silane

<1S(R),2S>-N-(2-hydroxy-1-methyl-2-phenylethyl)-4-(tert-butyldimethylsilyloxy)-N-methyl-2-(phenylmethyl)butanamide