1,2-O-Isopropylidene-beta-D-fructopyrase

Base Information

• Chemical Name: 1,2-O-Isopropylidene-beta-D-fructopyrase
• CAS No.: 66900-93-4
• Molecular Formula: C9H16O6
• Molecular Weight: 220.222
• Mol file: 66900-93-4.mol

Synonyms:Pentanoic acid,5-fluoro;1,2-O-Isopropylidene-Beta-D-fructopyranose;5-Fluorovaleric acid;Valeric acid,5-fluoro;

Chemical Property of 1,2-O-Isopropylidene-beta-D-fructopyrase

Chemical Property:

• PSA: 88.38000
• LogP: -1.42150
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

1,2-O-Isopropylidene-beta-D-Fructopyranose 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-O-Isopropylidene-beta-D-fructopyrase

There total 4 articles about 1,2-O-Isopropylidene-beta-D-fructopyrase which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose (25018-67-1) + methanol (67-56-1) → 1,2-O-isopropylidene-β-D-fructopyranose (66900-93-4) + methyl β-D-fructofuranoside (13403-14-0,15219-93-9,16975-88-5,51295-55-7,51295-56-8,52443-09-1,60504-77-0,60504-79-2,63526-47-6,69460-17-9,92283-23-3) + methyl α-D-fructofuranoside (13403-14-0,15219-93-9,16975-88-5,51295-55-7,51295-56-8,52443-09-1,60504-77-0,60504-79-2,63526-47-6,69460-17-9,92283-23-3)

Guidance literature:

With hydrogenchloride; at 20 ℃; for 16h;

DOI:10.1080/104265090508424

Reference yield:

acetone (67-64-1) + Sucrose (57-50-1) → 2,3;4,5-di-O-isopropylidene-β-D-fructopyranose (20880-92-6) + 1,2-O-isopropylidene-β-D-fructopyranose (66900-93-4) + 1,2-O-isopropylidene-α-D-glucofuranose (18549-40-1)

Guidance literature:

With acetic acid; iodine; Yield given. Multistep reaction. Yields of byproduct given; 1) reflux, 4 h, 2) room temp., 22 h;

DOI:10.1002/recl.19921110703

Reference yield:

→ 2,2-Dimethyl-1,3,6-trioxa-spiro[4.5]decane-8,9,10-triol (10583-34-3,18604-34-7,20789-58-6,41342-42-1,66900-93-4,83541-86-0,124338-71-2)

Guidance literature:

Sorbose, Acn./CuSO4;

DOI:10.1007/BF00760850

upstream raw materials:

D-melibiose

acetone

Sucrose

1,2;4,5-di-O-isopropylidene-β-D-(-)-fructopyranose

Downstream raw materials:

3,4,5-tri-O-benzyl-1,2-O-isopropylidene-β-D-fructopyranose

(R)-5-O-cyclohexylcarbamoyl-1,2-O-isopropylidene-3,4-O-(2,2,2-trichloroethylidene)-β-D-tagatopyranose

3,4,5-tri-O-benzoyl-β-D-fructopyranoside

C₂₇H₂₂O₈

Refernces

• 1、 Verhart, Cor G. J.,Caris, Brigitte M. G.,Zwanenburg, Binne,Chittenden, Gordon J. F.. "Acetalation studies. Part IX. Reaction of sucrose and some related sugars with acetone in the presence of iodine; a novel cleavage-isopropylidenation method". . p. 348 - 352. Retrieved 2007/10/02.