S-cyclohexyl ethanethioate

Base Information

• Chemical Name: S-cyclohexyl ethanethioate
• CAS No.: 10039-63-1
• Molecular Formula: C8H14OS
• Molecular Weight: 158.265
• Mol file: 10039-63-1.mol

Synonyms:

Chemical Property of S-cyclohexyl ethanethioate

Chemical Property:

• Vapor Pressure: 0.086mmHg at 25°C

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of S-cyclohexyl ethanethioate

There total 13 articles about S-cyclohexyl ethanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

tert-butyl(cyclohexyl)sulfane (7133-23-5) + acetyl chloride (75-36-5) → S-cyclohexyl ethanethioate (10039-63-1)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 0 - 20 ℃; for 1h; Reagent/catalyst; Green chemistry;

DOI:10.1039/c4ob02120g

Reference yield: 98.0%

Cyclohexanethiol (1569-69-3) + acetic anhydride (108-24-7) → S-cyclohexyl ethanethioate (10039-63-1)

Guidance literature:

With silica gel; for 0.05h; Microwave irradiation; neat (no solvent);

DOI:10.1080/10426507.2010.496277

Reference yield: 97.0%

tiolacetic acid (507-09-5) + cyclohexene (110-83-8) → S-cyclohexyl ethanethioate (10039-63-1)

Guidance literature:

With benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one; In cyclohexane; at 20 ℃; for 1h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/acs.joc.9b01331

upstream raw materials:

thioacetic acid

cyclohexene

tiolacetic acid

Acetyl bromide

Downstream raw materials:

Cyclohexanethiol

1,2-dicyclohexyl disulfide

acetic acid

(vinylsulfonyl)cyclohexane

Refernces

• 1、 Lakouraj, Moslem M.,Movassagh, Barahman,Fadaei, Zahra. "Convenient synthesis of thiol esters from acyl chlorides and disulfides using Zn/AlCl3". . p. 1085 - 1088. Retrieved 2002.
• 2、 Zarei, Amin,Hajipour, Abdol R.,Khazdooz, Leila. "P2O5/Al2O3 AS an efficient heterogeneous catalyst for the acetylation of alcohols, phenols, thiols, and amines under solvent-free conditions". . p. 1772 - 1785. Retrieved 2011.
• 3、 Veisi, Hojat,Ghorbani-Vaghei, Ramin,Eskandari, Hosna,Hemmati, Saba,Rezaei, Ardashir,Hajinazari, Somaye,Far, Mohammad Raoof Heidari,Entezari, Azam. "Poly-(N,N′-dibromo-N-ethyl-benzene-1,3-disulfonamide) and N,N,N′,N′- tetrabromobenzene-1,3-disulfonamide as highly efficient catalysts, and (AC2O/SIO2) as a heterogeneous system for the acetylation of alcohols, amines, and thiols under microwave irradiation". . p. 213 - 219. Retrieved 2011.
• 4、 Pijper, Thomas C.,Robertus, Jort,Browne, Wesley R.,Feringa, Ben L.. "Mild Ti-mediated transformation of t-butyl thio-ethers into thio-acetates". . p. 265 - 268. Retrieved 2014.
• 5、 McCourt, Ruairí O.,Scanlan, Eoin M.. "Atmospheric Oxygen Mediated Radical Hydrothiolation of Alkenes". supporting information. p. 15804 - 15810. Retrieved 2020/10/26.
• 6、 Kuciński, Krzysztof,Hreczycho, Grzegorz. "S-Acetylation of Thiols Mediated by Triflic Acid: A Novel Route to Thioesters". . p. 489 - 493. Retrieved 2018/04/27.