3-fluoro-5-methoxypicolinic acid methyl ester

Base Information

Chemical Name:3-fluoro-5-methoxypicolinic acid methyl ester
CAS No.:1256787-03-7
Molecular Formula:C₈H₈FNO₃
Molecular Weight:185.155
Hs Code.:

Synonyms:

Suppliers and Price of 3-fluoro-5-methoxypicolinic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Methyl3-Fluoro-5-methoxypicolinate
100mg
$ 265.00

Crysdot
Methyl3-fluoro-5-methoxypicolinate 95+%
5g
$ 1504.00

Crysdot
Methyl3-fluoro-5-methoxypicolinate 95+%
1g
$ 429.00

Chemenu
Methyl3-fluoro-5-methoxypicolinate 95%
1g
$ 405.00

Alichem
Methyl3-fluoro-5-methoxypicolinate
1g
$ 3039.75

Alichem
Methyl3-fluoro-5-methoxypicolinate
500mg
$ 1685.00

Total 9 raw suppliers

Chemical Property of 3-fluoro-5-methoxypicolinic acid methyl ester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Methyl3-Fluoro-5-methoxypicolinate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-fluoro-5-methoxypicolinic acid methyl ester

There total 5 articles about 3-fluoro-5-methoxypicolinic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 67-56-1
methanol

: 201230-82-2
carbon monoxide

: 2-chloro-3-fluoro-5-methoxypyridine

: 1256787-03-7
3-fluoro-5-methoxypicolinic acid methyl ester

Guidance literature:: With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine; at 110 ℃; for 6h; under 10343.2 Torr; Autoclave;

Reference yield: 37.0%

: 1402742-26-0
C₁₀H₁₁F₂NO₂

: 124-41-4
sodium methylate

: 1256787-03-7
3-fluoro-5-methoxypicolinic acid methyl ester

: 1402742-27-1
C₁₁H₁₄FNO₃

Guidance literature:: With methanol; at 25 ℃; for 1.5h;

Reference yield:

: 831203-13-5
5-bromo-2-chloro-3-fluoro-pyridine

: 1256787-03-7
3-fluoro-5-methoxypicolinic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: n-butyllithium / toluene; hexane / 0.33 h / -78 °C

1.2: 16 h / -78 - 20 °C

1.3: 2 h / 0 - 20 °C

2.1: potassium carbonate / acetone / 16 h / Reflux

3.1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; triethylamine / 6 h / 110 °C / 10343.2 Torr / Autoclave

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; n-butyllithium; potassium carbonate; triethylamine; In hexane; acetone; toluene;