(1S)-2-endo-chlorofenchane

Base Information

• Chemical Name: (1S)-2-endo-chlorofenchane
• CAS No.: 1195-77-3
• Molecular Formula: C₁₀H₁₇Cl
• Molecular Weight: 172.698
• Mol file: 1195-77-3.mol

Synonyms:

Chemical Property of (1S)-2-endo-chlorofenchane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1S)-2-endo-chlorofenchane

There total 2 articles about (1S)-2-endo-chlorofenchane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + diethyl ether (60-29-7,927820-24-4) + 2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol (35408-04-9) → (-)-α-pinene (7785-26-4,25766-18-1) + (1S)-2-endo-chlorofenchane (1195-77-3,3372-12-1,90976-73-1) + limonene. (138-86-3,555-08-8,8022-90-0,9003-73-0,95327-98-3)

Guidance literature:

Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge;

Reference yield:

(1R,5S)-(+)-nopinone (38651-65-9) → (1S)-2-endo-chlorofenchane (1195-77-3,3372-12-1,90976-73-1)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether

2: diethyl ether; hydrogen chloride / Erwaermen des Reaktionsprodukts mit aethanol. Kalilauge

With hydrogenchloride; diethyl ether;

Reference yield:

(1R,2S,4S)-exo-β-fenchyl chloride (1195-77-3,3372-12-1,90976-73-1) + triphenyltin chloride (639-58-7) → β-fenchyltriphenyltin (1110686-64-0,1110686-62-8) + α-fenchyltriphenyltin (1110686-64-0,1110686-62-8) + triphenyltin(IV) hydroxide (76-87-9)

Guidance literature:

With magnesium; In tetrahydrofuran; toluene; soln. of β-fenchyl chloride in THF wasadded to suspn. of Mg in THF,refluxed for 12 h, separated from Mg via cannula, Ph3SnCl was added; detected by 119Sn NMR;

DOI:10.1039/b819178f

upstream raw materials:

hydrogenchloride

diethyl ether

2,6,6-trimethylbicyclo[3.1.1]heptan-2-ol

(1R,5S)-(+)-nopinone

Downstream raw materials:

β-fenchyltriphenyltin

α-fenchyltriphenyltin

triphenyltin(IV) hydroxide