(+/-)-erythro-3-methylamino-2-phenyl-butane

Base Information

• Chemical Name: (+/-)-erythro-3-methylamino-2-phenyl-butane
• CAS No.: 64969-62-6
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.263
• Mol file: 64969-62-6.mol

Synonyms:

Chemical Property of (+/-)-erythro-3-methylamino-2-phenyl-butane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-erythro-3-methylamino-2-phenyl-butane

There total 6 articles about (+/-)-erythro-3-methylamino-2-phenyl-butane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Phenylpropanal (34713-70-7) → (+/-)-erythro-3-methylamino-2-phenyl-butane (64969-62-6)

Guidance literature:

Multi-step reaction with 2 steps

1: NaOAc / ethanol; H₂O

2: 2.) H₂ / 2.) 3percent Pd/C / 1.) ether, 0 deg C, 2.) MeOH

With hydrogen; sodium acetate; palladium on activated charcoal; In ethanol; water;

DOI:10.1039/c39880001503

Reference yield:

N-Methylformamide (123-39-7) + 3-phenyl-butan-2-one (769-59-5) → (+/-)-erythro-3-methylamino-2-phenyl-butane (64969-62-6)

Guidance literature:

beim Erhitzen des Reaktionsprodukts mit wss. Salzsaeure;

DOI:10.1021/ja01255a017

Reference yield:

methylmagnesium chloride (676-58-4) + N-(2-phenylpropylidene)-methylamine N-oxide (426822-59-5) → (+/-)-erythro-3-methylamino-2-phenyl-butane (64969-62-6) + Methyl-((1R,2S)-1-methyl-2-phenyl-propyl)-amine

Guidance literature:

With hydrogen; palladium on activated charcoal; Yield given. Multistep reaction. Yields of byproduct given; 1.) ether, 0 deg C, 2.) MeOH;

DOI:10.1039/c39880001503

upstream raw materials:

1,2-trans-dimethyl-2-phenylethylamine

methylmagnesium chloride

N-(2-phenylpropylidene)-methylamine N-oxide

N-Methylformamide