1-Benzoylpiperidine-4-carbaldehyde

Base Information

Chemical Name:1-Benzoylpiperidine-4-carbaldehyde
CAS No.:120014-29-1
Molecular Formula:C13H15NO2
Molecular Weight:217.268
Hs Code.:
DSSTox Substance ID:DTXSID10576781
Wikidata:Q82466643
Mol file:120014-29-1.mol

Synonyms:1-benzoylpiperidine-4-carbaldehyde;120014-29-1;SCHEMBL4893989;DTXSID10576781;FXFCQBKRSKWLPE-UHFFFAOYSA-N;1-benzoyl-4-piperidinecarbaldehyde;1-Benzoylpiperidine-4-carboxaldehyde;1-benzoyl-piperidine-4-carboxaldehyde;EN300-7385501

Suppliers and Price of 1-Benzoylpiperidine-4-carbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Benzoylpiperidine-4-carbaldehyde

Chemical Property:

XLogP3:1.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:217.110278721
Heavy Atom Count:16
Complexity:251

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CN(CCC1C=O)C(=O)C2=CC=CC=C2

Technology Process of 1-Benzoylpiperidine-4-carbaldehyde

There total 9 articles about 1-Benzoylpiperidine-4-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 19980-00-8
1-benzoyl-4-hydroxymethyl-piperidine

: 120014-29-1
1-benzoyl-piperidine-4-carboxaldehyde

Guidance literature:: With 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In ethyl acetate; for 5.5h; Reflux;
DOI:10.1002/anie.201807735

Reference yield:

: 79-37-8
oxalyl dichloride

: 19980-00-8
1-benzoyl-4-hydroxymethyl-piperidine

: 120014-29-1
1-benzoyl-piperidine-4-carboxaldehyde

Guidance literature:: With dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; In hexane; dichloromethane; water;

Reference yield:

: 1126-09-6
4-carbethoxypiperidine

: 120014-29-1
1-benzoyl-piperidine-4-carboxaldehyde

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / CH₂Cl₂ / 0 °C

2: lithium aluminum hydride / tetrahydrofuran / 0 °C

3: pyridinium chlorochromate; Celite / CH₂Cl₂ / 20 °C

With lithium aluminium tetrahydride; Celite; triethylamine; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.tetlet.2006.11.072