1-(2-Bromoethoxy)naphthalene

Base Information

• Chemical Name: 1-(2-Bromoethoxy)naphthalene
• CAS No.: 13247-79-5
• Molecular Formula: C12H11BrO
• Molecular Weight: 251.123
• Hs Code.: 2909309090
• European Community (EC) Number: 837-128-9
• DSSTox Substance ID: DTXSID00927703
• Nikkaji Number: J708.414E
• Wikidata: Q82902345
• Mol file: 13247-79-5.mol

Synonyms:1-(2-bromoethoxy)naphthalene;13247-79-5;Naphthalene, 1-(2-bromoethoxy)-;2-bromoethyl naphthyl ether;1-(2-bromoethoxyl)naphthalene;2-(1-naphthoxy) ethylbromide;SCHEMBL2204553;2-(1-naphthyloxy)ethyl bromide;DTXSID00927703;OBGFJKNQKBMXBM-UHFFFAOYSA-N;AKOS000170383;CS-0216728;EN300-56159;InChI=1/C12H11BrO/c13-8-9-14-12-7-3-5-10-4-1-2-6-11(10)12/h1-7H,8-9H

Chemical Property of 1-(2-Bromoethoxy)naphthalene

Chemical Property:

• PSA: 9.23000
• LogP: 3.61350
• Storage Temp.: 2-8°C
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 249.99933
• Heavy Atom Count: 14
• Complexity: 172

Purity/Quality:

99% ^*data from raw suppliers

1-(2-bromoethoxy)naphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2OCCBr

Technology Process of 1-(2-Bromoethoxy)naphthalene

There total 4 articles about 1-(2-Bromoethoxy)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

α-naphthol (90-15-3) + 2-bromoethanol (540-51-2) → 1-(2-bromoethoxy)naphthalene (13247-79-5)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 0 - 20 ℃; for 4.25h; Inert atmosphere;

DOI:10.1016/j.bmcl.2021.128215

Reference yield: 67.0%

α-naphthol (90-15-3) + ethylene dibromide (106-93-4) → 1-(2-bromoethoxy)naphthalene (13247-79-5)

Guidance literature:

With sodium hydroxide; for 6.5h; Heating;

Reference yield: 48.0%

→ 1-(2-bromoethoxy)naphthalene (13247-79-5)

Guidance literature:

With sodium hydroxide; In water; at 130 ℃; for 16h;

upstream raw materials:

α-naphthol

ethylene dibromide

β-naphthol

2-bromoethanol

Downstream raw materials:

4--1-<2-(1-naphthalenyloxy)ethyl>piperidine

Benzyl-methyl-[2-(naphthalen-1-yloxy)-ethyl]-amine

α-naphthol

N-[2-(naphth-1-yl-oxy)ethyl]-p-nitrophenethylamine