2-Chloro-5-methoxy-4-methylaniline

Base Information

Chemical Name:2-Chloro-5-methoxy-4-methylaniline
CAS No.:133088-44-5
Molecular Formula:C8H10ClNO
Molecular Weight:171.626
Hs Code.:
DSSTox Substance ID:DTXSID20563900
Nikkaji Number:J373.458G
Wikidata:Q82448407

Synonyms:2-chloro-5-methoxy-4-methylaniline;133088-44-5;2-Chloro-5-methoxy-4-methyl-phenylamine;SCHEMBL5257080;DTXSID20563900;G11246

Suppliers and Price of 2-Chloro-5-methoxy-4-methylaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Chloro-5-methoxy-4-methylaniline

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:171.0450916
Heavy Atom Count:11
Complexity:131

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1OC)N)Cl

Technology Process of 2-Chloro-5-methoxy-4-methylaniline

There total 2 articles about 2-Chloro-5-methoxy-4-methylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 7206-70-4
4-amino-5-chloro-2-methoxybenzoic acid

: 133088-44-5
2-chloro-5-methoxy-4-methylaniline

Guidance literature:: With dimethylsulfide borane complex; In chlorobenzene; at 80 - 130 ℃; for 21h;
DOI:10.1021/jo061749g

Reference yield: 65.0%

: 7206-70-4
4-amino-5-chloro-2-methoxybenzoic acid

: 13292-87-0
dimethylsulfide borane complex

: 133088-44-5
2-chloro-5-methoxy-4-methylaniline

Guidance literature:: In chlorobenzene; at 80 - 130 ℃; for 21h; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02552

Reference yield: 99.0%

: 460-00-4
1-Bromo-4-fluorobenzene

: 133088-44-5
2-chloro-5-methoxy-4-methylaniline

: 2-chloro-N-(4-fluorophenyl)-5-methoxy-4-methylaniline

Guidance literature:: With palladium diacetate; sodium t-butanolate; tri tert-butylphosphoniumtetrafluoroborate; In toluene; for 18h; Reflux; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02552