pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate

Base Information

• Chemical Name: pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate
• CAS No.: 220015-49-6
• Molecular Formula: C₂₉H₁₈F₅FeO₂P
• Molecular Weight: 580.273
• Mol file: 220015-49-6.mol

Synonyms:

Chemical Property of pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate

There total 1 articles about pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1′-(diphenylphosphino)ferrocene-1-carboxylic acid (173346-69-5) + 2,3,4,5,6-pentafluorophenol (771-61-9) → pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate (220015-49-6)

Guidance literature:

With N-ethyl-N'-[3-(dimethylamino)propyl]carbodiimide; 4-(dimethylamino)pyridine; In dichloromethane; (N2); dissolving of (PPh2C5H4)Fe(C5H4COOH), C6F5OH, N-ethyl-N'-(3-(dimethylamino)propyl)carbodiimide and 4-(dimethylamino)pyridine in CH2Cl2; stirring at room temp. for 20 h; washing with brine; drying over MgSO4; evapn., chromy. (silica gel, hexane-Et2O 1:1 v/v); evapn.;

DOI:10.1016/j.jorganchem.2009.04.007

Reference yield: 89.0%

dichloromethane (75-09-2) + Tau (107-35-7) + pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate (220015-49-6) + triethylamine (121-44-8) → [triethylammonium][Fe(C5H4P(C6H5)2)(C5H4CONHCH2CH2SO3)]*0.1dichloromethane

Guidance literature:

With catalyst: (CH₃)2NC₅H₄N; H₂O; In triethylamine; N,N-dimethyl-formamide; (Ar, dark); dissolving ferrocene deriv., aminomethanesulfonic acid and pyridine deriv. in DMF/triethylamine (10:1), stirring at room temp. for 30 min, addn. of distd. water, stirring for 20 h; evapn., extn. (CH2Cl2), drying over MgSO4, evapn., chromy. (silica gel, CH2Cl2/methanol/triethylamine (100:5:2)), evapn., dissolving in boiling ethyl acetate, cooling to -4°C, suction, drying in vac., elem. anal.;

DOI:10.1021/om2011529

Reference yield: 82.0%

aminomethanesulfonic acid (13881-91-9) + pentafluorophenyl 1-(diphenylphosphanyl)ferrocene-1-carboxylate (220015-49-6) + triethylamine (121-44-8) → [triethylammonium][Fe(C5H4P(C6H5)2)(C5H4CONHCH2SO3)] (1353868-75-3)

Guidance literature:

With catalyst: (CH₃)2NC₅H₄N; In triethylamine; N,N-dimethyl-formamide; (Ar, dark); dissolving ferrocene deriv., aminomethanesulfonic acid and pyridine deriv. in DMF/triethylamine, stirring at room temp. for 6 h; evapn., extn. (CH2Cl2) under sonication, filtration, evapn., chromy. (silica gel, CH2Cl2/methanol/triethylamine (100:5:2)), evapn., recrystn. (hot ethyl acetate), suction, drying in vac., elem. anal.;

DOI:10.1021/om2011529

upstream raw materials:

1′-(diphenylphosphino)ferrocene-1-carboxylic acid

2,3,4,5,6-pentafluorophenol

Downstream raw materials:

[triethylammonium][Fe(C₅H₄P(C₆H₅)2)(C₅H₄CONHCH₂SO₃)]