3-BroMo-4-pivalaMidobenzoic acid

Base Information

• Chemical Name: 3-BroMo-4-pivalaMidobenzoic acid
• CAS No.: 139058-18-7
• Molecular Formula: C₁₂H₁₄BrNO₃
• Molecular Weight: 300.152
• Mol file: 139058-18-7.mol

Synonyms:3-bromo-4-(2,2-dimethylpropanoylamino)benzoic acid;

Chemical Property of 3-BroMo-4-pivalaMidobenzoic acid

Chemical Property:

• PSA: 69.89000
• LogP: 3.78140
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

3-Bromo-4-pivalamidobenzoicacid 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-BroMo-4-pivalaMidobenzoic acid

There total 3 articles about 3-BroMo-4-pivalaMidobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

N-(2-bromo-4-methylphenyl)-2,2-dimethylpropanamide (87995-50-4) → 3-bromo-4-(2,2-dimethylpropanoylamino)benzoic acid (139058-18-7)

Guidance literature:

With potassium permanganate; magnesium sulfate; In water; for 1h; Heating;

Reference yield:

2-bromo-p-toluidine (583-68-6) → 3-bromo-4-(2,2-dimethylpropanoylamino)benzoic acid (139058-18-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / diethyl ether / 1 h

2: 40 percent / KMnO₄, MgSO₄ / H₂O / 1 h / Heating

With potassium permanganate; magnesium sulfate; In diethyl ether; water;

Reference yield:

pivaloyl chloride (3282-30-2) → 3-bromo-4-(2,2-dimethylpropanoylamino)benzoic acid (139058-18-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / diethyl ether / 1 h

2: 40 percent / KMnO₄, MgSO₄ / H₂O / 1 h / Heating

With potassium permanganate; magnesium sulfate; In diethyl ether; water;

upstream raw materials:

N-(2-bromo-4-methylphenyl)-2,2-dimethylpropanamide

2-bromo-p-toluidine

pivaloyl chloride

Downstream raw materials:

4-(2,2-dimethylpropanoylamino)-3-iodobenzoic acid

Refernces