2-methoxy-3,6-dimethylhydroquinone

Base Information

• Chemical Name: 2-methoxy-3,6-dimethylhydroquinone
• CAS No.: 99892-95-2
• Molecular Formula: C₉H₁₂O₃
• Molecular Weight: 168.192
• Mol file: 99892-95-2.mol

Synonyms:

Chemical Property of 2-methoxy-3,6-dimethylhydroquinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-3,6-dimethylhydroquinone

There total 5 articles about 2-methoxy-3,6-dimethylhydroquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxy-3,6-dimethyl-1,4-benzoquinone (2913-45-3) → 2-methoxy-3,6-dimethylhydroquinone (99892-95-2)

Guidance literature:

With sodium dithionite; In diethyl ether; water; for 2h;

DOI:10.1248/cpb.33.2122

Reference yield:

2,4-dimethoxy-3-methylphenol (19676-67-6) → 2-methoxy-3,6-dimethylhydroquinone (99892-95-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 66 percent / acetic acid / 2 h / Heating

2: 86 percent / hydrazine hydrate, KOH / 1.) reflux, 15 min; 2.) 120 deg C, 30 min; 3.) 140 deg C, 30 min

3: 77 percent / ceric ammonium nitrate / H₂O; acetonitrile / 0.75 h / Ambient temperature

4: sodium dithionite / H₂O; diethyl ether / 2 h

With potassium hydroxide; sodium dithionite; ammonium cerium(IV) nitrate; hydrazine hydrate; In diethyl ether; water; acetic acid; acetonitrile;

DOI:10.1248/cpb.33.2122

Reference yield:

2,4-dimethoxy-3,6-dimethylphenol (53887-75-5) → 2-methoxy-3,6-dimethylhydroquinone (99892-95-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 77 percent / ceric ammonium nitrate / H₂O; acetonitrile / 0.75 h / Ambient temperature

2: sodium dithionite / H₂O; diethyl ether / 2 h

With sodium dithionite; ammonium cerium(IV) nitrate; In diethyl ether; water; acetonitrile;

DOI:10.1248/cpb.33.2122

upstream raw materials:

2-methoxy-3,6-dimethyl-1,4-benzoquinone

acetic acid

2,4-dimethoxy-3-methylphenol

2,4-dimethoxy-3,6-dimethylphenol

Downstream raw materials:

4,7-dibenzyloxy-5-methoxy-6-methylindole

2-methoxy-3,6-dimethyl-5-nitrohydroquinone dibenzyl ether

(2,5-dibenzyloxy-3-methoxy-4-methyl-6-nitrophenyl)acetaldehyde

2-methoxy-3,6-dimethylhydroquinone dibenzyl ether