2-benzoylnaphtho[2,1-b]furan oxime

Base Information

• Chemical Name: 2-benzoylnaphtho[2,1-b]furan oxime
• CAS No.: 771487-92-4
• Molecular Formula: C₁₉H₁₃NO₂
• Molecular Weight: 287.318
• Mol file: 771487-92-4.mol

Synonyms:

Chemical Property of 2-benzoylnaphtho[2,1-b]furan oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzoylnaphtho[2,1-b]furan oxime

There total 5 articles about 2-benzoylnaphtho[2,1-b]furan oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

naphtho[2,1-b]furan-2-yl phenyl methanone (94830-76-9) → 2-benzoylnaphtho[2,1-b]furan oxime (771487-92-4)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In ethanol; for 3h; Reflux;

Reference yield: 78.0%

hydroxylamine hydrochloride (5470-11-1) + naphtho[2,1-b]furan-2-yl phenyl methanone (94830-76-9) → 2-benzoylnaphtho[2,1-b]furan oxime (771487-92-4)

Guidance literature:

With sodium acetate; In ethanol; for 3h; Reflux;

Reference yield:

acetophenone (98-86-2) → 2-benzoylnaphtho[2,1-b]furan oxime (771487-92-4)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrogen bromide; bromine / acetic acid / 1 h / Cooling with ice

2: potassium carbonate / acetonitrile / 8 h / Reflux

3: sodium acetate / ethanol / 3 h / Reflux

With hydrogen bromide; bromine; sodium acetate; potassium carbonate; In ethanol; acetic acid; acetonitrile; 2: Rap-Stoermer reaction;

upstream raw materials:

hydroxylamine hydrochloride

naphtho[2,1-b]furan-2-yl phenyl methanone

acetophenone

α-bromoacetophenone

Downstream raw materials:

C₂₁H₁₅NO₃