C₁₉H₂₇NO₃

Base Information

Chemical Name:C₁₉H₂₇NO₃
CAS No.:1381929-92-5
Molecular Formula:C₁₉H₂₇NO₃
Molecular Weight:317.428
Hs Code.:

C<sub>19</sub>H<sub>27</sub>NO<sub>3</sub>

Synonyms:

Suppliers and Price of C₁₉H₂₇NO₃

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
trans-Tetrabenazine
10 mg
$ 2120.00

Crysdot
(3S,11BR)-3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one 97%
1g
$ 762.00

Crysdot
(3S,11BR)-3-isobutyl-9,10-dimethoxy-3,4,6,7-tetrahydro-1H-pyrido[2,1-a]isoquinolin-2(11bH)-one 97%
250mg
$ 305.00

Total 6 raw suppliers

Chemical Property of C₁₉H₂₇NO₃

Chemical Property:

Purity/Quality:

> 95% ^*data from raw suppliers

trans-Tetrabenazine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses trans-Tetrabenazine is the trans isomer of Tetrabenazine (T284000); a dopamine depleting agent, an antidyskinetic and antipsychotic.

Technology Process of C₁₉H₂₇NO₃

There total 93 articles about C₁₉H₂₇NO₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 67-56-1
methanol

: 89929-27-1
(+/-)-9,10-dihydroxy-3c-isobutyl-(11br)-1,3,4,6,7,11b-hexahydro-pyrido[2,1-a]isoquinolin-2-one

: 58-46-8,1381929-92-5
(3R^*,11bR^*)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo quinolizin-2-one

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 25 - 30 ℃; Large scale;
DOI:10.1021/acs.oprd.8b00011

Reference yield: 75.0%

: 3382-18-1
6,7-dimethoxy-3,4-dihydro-isoquinoline

: 1069-62-1
trimethyl[2-(2-methylpropyl)-3-oxobutyl]azanium iodide

: 58-46-8,1381929-92-5
(3R^*,11bR^*)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo quinolizin-2-one

Guidance literature:: 6,7-dimethoxy-3,4-dihydro-isoquinoline; trimethyl[2-(2-methylpropyl)-3-oxobutyl]azanium iodide; In ethanol; at 80 ℃;

With sodium hydroxide; water; In dichloromethane;

Reference yield: 69.0%

: 3382-18-1
6,7-dimethoxy-3,4-dihydro-isoquinoline

: C₁₂H₁₈O₃

: 58-46-8,1381929-92-5
(3R^*,11bR^*)-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo quinolizin-2-one

Guidance literature:: 6,7-dimethoxy-3,4-dihydro-isoquinoline; C₁₂H₁₈O₃; In ethanol; at 60 ℃; for 72h; Inert atmosphere;

With morpholine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; ethanol; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1039/c9ob01880h