6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine

Base Information

• Chemical Name: 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine
• CAS No.: 75104-96-0
• Molecular Formula: C₉H₉BrN₂S
• Molecular Weight: 257.154
• Mol file: 75104-96-0.mol

Synonyms:

Chemical Property of 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

6-Bromo-N,N-dimethyl-1,3-benzothiazol-2-amine 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 6-bromo-N,N-dimethyl-1,3-benzothiazol-2-amine can be used to treat or prevent tau aggregate disorders.

Technology Process of 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine

There total 15 articles about 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

6-bromo-2-chloro-benzothiazole (80945-86-4) + dimethyl amine (124-40-3) → 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine (75104-96-0)

Guidance literature:

In ethanol; at 100 ℃; for 1h; Microwave irradiation;

Reference yield: 88.0%

4-bromo-2-iodoaniline (66416-72-6) + sodium dimethyldithiocarbamate (128-04-1) → 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine (75104-96-0)

Guidance literature:

With copper diacetate; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 6h; Sealed tube;

DOI:10.1002/ejoc.201801122

Reference yield: 86.0%

4-bromo-2-iodoaniline (66416-72-6) + N,N-Dimethylthiocarbamoyl chloride (16420-13-6) → 6-bromo-N,N-dimethylbenzo[d]thiazol-2-amine (75104-96-0)

Guidance literature:

With potassium tert-butylate; copper(I) bromide; In tetrahydrofuran; at 60 ℃; for 4h; Schlenk technique;

DOI:10.1080/00397911.2017.1324033

upstream raw materials:

N_⁽¹⁾-(4-bromophenyl)-N,N-dimethylthiourea

chloroform

N,N-dimethyl-N'-phenylthiourea

4-Bromophenyl isothiocyanate